ID   CCD22_AEDAE             Reviewed;         589 AA.
AC   Q16VW9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Coiled-coil domain-containing protein 22 homolog;
GN   ORFNames=AAEL009388;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1] {ECO:0000312|EMBL:EAT38744.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SIMILARITY: Belongs to the CCDC22 family. {ECO:0000255}.
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DR   EMBL; CH477579; EAT38744.1; -; Genomic_DNA.
DR   RefSeq; XP_001660026.1; XM_001659976.1.
DR   AlphaFoldDB; Q16VW9; -.
DR   SMR; Q16VW9; -.
DR   STRING; 7159.AAEL009388-PA; -.
DR   PRIDE; Q16VW9; -.
DR   GeneID; 5571929; -.
DR   KEGG; aag:5571929; -.
DR   VEuPathDB; VectorBase:AAEL009388; -.
DR   eggNOG; KOG1937; Eukaryota.
DR   HOGENOM; CLU_024231_1_0_1; -.
DR   InParanoid; Q16VW9; -.
DR   OMA; KFEQHIQ; -.
DR   OrthoDB; 985190at2759; -.
DR   PhylomeDB; Q16VW9; -.
DR   Proteomes; UP000008820; Chromosome 3.
DR   InterPro; IPR008530; CCDC22.
DR   PANTHER; PTHR15668; PTHR15668; 1.
DR   Pfam; PF05667; DUF812; 2.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..589
FT                   /note="Coiled-coil domain-containing protein 22 homolog"
FT                   /id="PRO_0000347255"
FT   REGION          568..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          287..426
FT                   /evidence="ECO:0000255"
FT   COILED          523..589
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        570..589
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   589 AA;  66487 MW;  43A6A6565A011EF2 CRC64;
     MDEIDNIILH SLRQIECNLD EEVISLDDLS PSMLVQVVSK CISLIDPGLE LPRTLPPGMA
     QRFTATASLA EACRTIGYRR DIGYQTFLYS NVAEVRRVLM FLVEKLPKEA ADKTSGSGQP
     VDSATQLENR ILSSLQSQLQ APWMPEFCQV GRPEGLSTTS GGESPAQIAF RRFIPRKISV
     PFVTQGDVAA EVKEFWSRRN LDCLDEGSLV PSLIAANDGA IKTNAKGAID EVDRQVKLPA
     INEKLLQYYS KGGTKHRLAE PSGAAASSGT TEKVVLNNIT VETKPGKTPL ESLQEEIDAL
     QQEIVQHSEE GVQLESSRKE TDESIEEYRK TIVRLKEEKK IKERTHILLE DPEVNVKKLE
     AIIAAGGERM KKLQDQWDAH RIPLVDTLEA YRLKNSDKLS KSQQVLDQIE STRQKCEEVV
     IDLQTKGAMY ARLQKEFEKL NKTVSRTAYT SRILEIIGNI RKQKNGIDQI LQDTRSLQKE
     INNITGQLDR QFTVTDDLIF RNAKKDEHSK RAYKLLVTLH SDCEELIKLV QETGAIKREV
     RDLEDQIENE KGRNTAANLA QITHDLTEMQ NESQRLEESI RRMEVTSRQ