ID   CCD22_DICDI             Reviewed;         637 AA.
AC   Q54MP2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Coiled-coil domain-containing protein 22 homolog;
GN   ORFNames=DDB_G0285813;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the CCDC22 family. {ECO:0000305}.
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DR   EMBL; AAFI02000080; EAL64528.1; -; Genomic_DNA.
DR   RefSeq; XP_638035.1; XM_632943.1.
DR   AlphaFoldDB; Q54MP2; -.
DR   SMR; Q54MP2; -.
DR   STRING; 44689.DDB0186696; -.
DR   PaxDb; Q54MP2; -.
DR   PRIDE; Q54MP2; -.
DR   EnsemblProtists; EAL64528; EAL64528; DDB_G0285813.
DR   GeneID; 8625299; -.
DR   KEGG; ddi:DDB_G0285813; -.
DR   dictyBase; DDB_G0285813; -.
DR   eggNOG; KOG1937; Eukaryota.
DR   HOGENOM; CLU_024231_1_0_1; -.
DR   InParanoid; Q54MP2; -.
DR   OMA; KFEQHIQ; -.
DR   PhylomeDB; Q54MP2; -.
DR   Reactome; R-DDI-8951664; Neddylation.
DR   PRO; PR:Q54MP2; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR   GO; GO:2000060; P:positive regulation of ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   InterPro; IPR008530; CCDC22.
DR   PANTHER; PTHR15668; PTHR15668; 1.
DR   Pfam; PF05667; DUF812; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..637
FT                   /note="Coiled-coil domain-containing protein 22 homolog"
FT                   /id="PRO_0000338403"
FT   COILED          322..489
FT                   /evidence="ECO:0000255"
FT   COILED          608..637
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   637 AA;  73539 MW;  87E7A98F08AE3DD1 CRC64;
     MDEADGIILI TLKDLGCEIE ENETIKNFDS EMVYKCILAY LRVINEQKVI NLTNTLPKNM
     SARVNACSLI ANIIKDSGYR SELSYHNLLY PNVNDIRKIF IFLGQLLPKK EVESGGVSIQ
     KLEDQICQYL QGCVKESWIP YFCPFSKRIP GNYSTATLFT TTGGNLRIPS RGRQLKVTPG
     LEQYYSQYLE PLTLQTNRFE DIAPSVFEYN LSIYAEAQER DNEWNDKGVS SGMNPIDYRK
     NKQKQVLSKM NDSIRQSIID GGNNQISSNC NSGDSFLDII SEFRGNSLDV GGQFNRKKAF
     TNELNNNNNN NNDSTTNTNK VETEIETEEQ RQLKRQAEID ALQSQIDEIS ESIQLHNKEM
     LDFLSLMRQS ESENLEQDQQ REVLEKQYKI KKKTFSLLDD AEGNMKELQS LCNQTSSNLL
     EMSGEWEKVR KPIIEKYRSL KDKQNNQADE TKSKLDRIKE MRILIKKLVS EVQQKDDQFQ
     QLQDQYKQAP KDSNRSQYTR RILETVKNIK KQKVDIDKVL LDTKNLQKEI NTITDTAVRT
     FELVKDLLYN DAKKDQTAKQ AIKSFAIIDD KFQKLFKTID ETGNFQNNIL NLNSKIEHVS
     QKTNTLNSDR VVQDLKNIKS ENQSLIKQIK TLIETKN