ID   CCD22_NEMVE             Reviewed;         644 AA.
AC   A7RNG8;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Coiled-coil domain-containing protein 22 homolog;
GN   ORFNames=v1g180167;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- SIMILARITY: Belongs to the CCDC22 family. {ECO:0000305}.
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DR   EMBL; DS469522; EDO47059.1; -; Genomic_DNA.
DR   RefSeq; XP_001639122.1; XM_001639072.1.
DR   AlphaFoldDB; A7RNG8; -.
DR   SMR; A7RNG8; -.
DR   STRING; 45351.EDO47059; -.
DR   EnsemblMetazoa; EDO47059; EDO47059; NEMVEDRAFT_v1g180167.
DR   GeneID; 5519222; -.
DR   KEGG; nve:5519222; -.
DR   eggNOG; KOG1937; Eukaryota.
DR   HOGENOM; CLU_024231_1_0_1; -.
DR   InParanoid; A7RNG8; -.
DR   OMA; KFEQHIQ; -.
DR   OrthoDB; 985190at2759; -.
DR   PhylomeDB; A7RNG8; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR   GO; GO:2000060; P:positive regulation of ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   InterPro; IPR008530; CCDC22.
DR   PANTHER; PTHR15668; PTHR15668; 1.
DR   Pfam; PF05667; DUF812; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..644
FT                   /note="Coiled-coil domain-containing protein 22 homolog"
FT                   /id="PRO_0000338404"
FT   REGION          316..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          333..383
FT                   /evidence="ECO:0000255"
FT   COILED          409..486
FT                   /evidence="ECO:0000255"
FT   COILED          592..644
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   644 AA;  73226 MW;  71200921C3B3D3C8 CRC64;
     MEEVDNIIIH TLRQIGCEIP EEIQSLREFT TTVIVQASSK CLHVINEDID IPSNLPSSMS
     AKFRVGTMLA AALQDLGYRG EIGYQTFLYS NEKDIRSVFM FLVEHLPKET SLAASEPLGS
     SVLLNRRVAS DLAQRLTLSW TPTFLKKGGV RWKGSKPKTY FREGSASMRR FHACNLKSPQ
     GLTDLTAKIS KETKAYYSVI PYVTSQPPCR QDVVPSVLES NSLSVTAVAE WELEWNQSGL
     SSRLTKEEYL ARKRQRLEKK IKDHVLAEMQ RVEAGGRAAS DLSDIVSSFS DRVSTIESQT
     QGSRFTRTEK LQFAQDEQKA AAMAGLSESG PPKMDTEEEL QKKREQELEA LQNKLKDLAS
     SVDEKKSEIK TMNAGLQQTN EQVTATKVQN SEHEESYKVK KRTVDLLPDA ENNIAKLQGV
     VDSSSQRLVN LAQQWETHRT ALIDEYRELK VINANKVSET QKKLEEIKSL REKMKEVAEE
     TRGKDDLYKQ LVSEYERMSR DVNRSAYTRR ILEIVGNIKK QKEEINKILV DTKSVQKEIN
     QLSGKLDRTF TVTDELIFRD AKKDEACRKA YKYLASLHEN CKELIQAVED TGVIMREIRD
     LEEQIDTESQ RNTANNLERI TADHKQMKEE NATLTKKIKA LKSS