ID   CCD22_XENLA             Reviewed;         632 AA.
AC   Q6PA15;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Coiled-coil domain-containing protein 22;
GN   Name=ccdc22;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in regulation of NF-kappa-B signaling. May be
CC       involved in copper-dependent atp7a trafficking between the trans-Golgi
CC       network and vesicles in the cell periphery (By similarity).
CC       {ECO:0000250|UniProtKB:O60826}.
CC   -!- SIMILARITY: Belongs to the CCDC22 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC060491; AAH60491.1; -; mRNA.
DR   RefSeq; NP_001083358.1; NM_001089889.1.
DR   AlphaFoldDB; Q6PA15; -.
DR   SMR; Q6PA15; -.
DR   DNASU; 398883; -.
DR   GeneID; 398883; -.
DR   KEGG; xla:398883; -.
DR   CTD; 398883; -.
DR   Xenbase; XB-GENE-979502; ccdc22.S.
DR   OrthoDB; 985190at2759; -.
DR   Proteomes; UP000186698; Chromosome 8S.
DR   Bgee; 398883; Expressed in testis and 19 other tissues.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008530; CCDC22.
DR   PANTHER; PTHR15668; PTHR15668; 1.
DR   Pfam; PF05667; DUF812; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Protein transport; Reference proteome; Transport;
KW   Ubl conjugation pathway.
FT   CHAIN           1..632
FT                   /note="Coiled-coil domain-containing protein 22"
FT                   /id="PRO_0000338401"
FT   COILED          243..269
FT                   /evidence="ECO:0000255"
FT   COILED          326..367
FT                   /evidence="ECO:0000255"
FT   COILED          400..540
FT                   /evidence="ECO:0000255"
FT   COILED          584..628
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   632 AA;  72251 MW;  9E046FA7DAB26279 CRC64;
     MEEVDRILIH SLRSCGTEVP EDIQSIRQFN TELIVEAVVR CLRVINPSLG ATLSHVLPPG
     MSAQFRIGTS LAQACQDLGY SSEVGYQTFL YSSEPDIRAL LIFLAEKLPR DSSEDAHQPA
     GKSALLQREI VATIKQQLSL PWLPLSCRIA ALRRSQSSCR LHRFHSQPLS LASDPALKSI
     PNERKEYWQR YLPSVTSQLP HLPSVAASLL ERNTSKLSAV QEWEAEWKSQ GLASRLSPED
     YRSKKQQRLQ KRIQEQLRQC AQLLAENHLP SSSSQDLTDM LRAFNLDGGS DQKKGSRFTR
     TQRFTYQQDP HTLKEQMQRA AEILPKKDAQ DADAEQQEIS SLQEQIDSIE QEIRGLSESN
     KLLQLTIGQV EGEVNDMHQS CEEKANVVRV KKRAVELLPD ADNNLDKLQT LVDASAQRMA
     NLIGQWESHQ ARLSDEYMEL NRVQQEQEDE SSRWMKDAKD LYEKIQGSAD EAKRKEELYK
     QLLSEYESLP KEVSRAAYTQ RILEIVSNIK KQKEEITKIL SDTKELQKEI NNLTGKVDRT
     FVVTDELVFK DAKKDEPVRK AYKYLAALHE NCSQLIQTIE DTGTILREIR DLEEQIETET
     TKKTLSNLQK ILEDYRAIKQ ENAQLLARTR EA