CCD25_DICDI
ID CCD25_DICDI Reviewed; 206 AA.
AC Q55D55;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Coiled-coil domain-containing protein 25 homolog;
GN Name=ccdc25; ORFNames=DDB_G0269786;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q86WR0}; Single-
CC pass membrane protein {ECO:0000250|UniProtKB:Q86WR0}.
CC -!- SIMILARITY: Belongs to the CCDC25 family. {ECO:0000305}.
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DR EMBL; AAFI02000005; EAL72243.1; -; Genomic_DNA.
DR RefSeq; XP_646276.1; XM_641184.1.
DR AlphaFoldDB; Q55D55; -.
DR STRING; 44689.DDB0304990; -.
DR PaxDb; Q55D55; -.
DR PRIDE; Q55D55; -.
DR EnsemblProtists; EAL72243; EAL72243; DDB_G0269786.
DR GeneID; 8617232; -.
DR KEGG; ddi:DDB_G0269786; -.
DR dictyBase; DDB_G0269786; ccdc25.
DR eggNOG; KOG3272; Eukaryota.
DR HOGENOM; CLU_076656_0_1_1; -.
DR InParanoid; Q55D55; -.
DR OMA; DVWFHVH; -.
DR PhylomeDB; Q55D55; -.
DR PRO; PR:Q55D55; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR039730; Jlp2/Ccd25.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR13049; PTHR13049; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..206
FT /note="Coiled-coil domain-containing protein 25 homolog"
FT /id="PRO_0000328428"
FT TOPO_DOM 1..34
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 35..51
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 52..206
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT REGION 138..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..182
FT /evidence="ECO:0000255"
SQ SEQUENCE 206 AA; 24874 MW; 66B77E9626B9E159 CRC64;
MVLYFKLIDP EYICYMGIDK FENEDLIKYG WPEDVWFHVN DLSSAHVYLR LRKGETWNDI
PANILEECCQ LVKQNSIQGC KEASVDIVYT PWANLKKTAG MEAGQVLYHN EREVKYVRNV
RKDSKIINRI EKTREKREVD LMHERDSRDK SERHEKRKEQ EEKRRAEKKA YEEKQKMEDI
KKYTSIMKTD NMKFNKYNPT DEDDFM