CCD27_MOUSE
ID CCD27_MOUSE Reviewed; 639 AA.
AC Q3V036;
DT 02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Coiled-coil domain-containing protein 27;
GN Name=Ccdc27; Synonyms=Gm1035;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
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DR EMBL; AK133459; BAE21669.1; -; mRNA.
DR CCDS; CCDS19008.1; -.
DR RefSeq; NP_001028627.1; NM_001033455.2.
DR AlphaFoldDB; Q3V036; -.
DR SMR; Q3V036; -.
DR BioGRID; 237998; 1.
DR CORUM; Q3V036; -.
DR STRING; 10090.ENSMUSP00000039642; -.
DR iPTMnet; Q3V036; -.
DR PhosphoSitePlus; Q3V036; -.
DR PaxDb; Q3V036; -.
DR PRIDE; Q3V036; -.
DR ProteomicsDB; 281304; -.
DR Antibodypedia; 52630; 47 antibodies from 9 providers.
DR Ensembl; ENSMUST00000047207; ENSMUSP00000039642; ENSMUSG00000039492.
DR GeneID; 381580; -.
DR KEGG; mmu:381580; -.
DR UCSC; uc008wbf.1; mouse.
DR CTD; 148870; -.
DR MGI; MGI:2685881; Ccdc27.
DR VEuPathDB; HostDB:ENSMUSG00000039492; -.
DR eggNOG; ENOG502RXSM; Eukaryota.
DR GeneTree; ENSGT00940000154171; -.
DR HOGENOM; CLU_025625_0_0_1; -.
DR InParanoid; Q3V036; -.
DR OMA; MRPGCPQ; -.
DR OrthoDB; 814498at2759; -.
DR PhylomeDB; Q3V036; -.
DR TreeFam; TF335685; -.
DR BioGRID-ORCS; 381580; 1 hit in 71 CRISPR screens.
DR PRO; PR:Q3V036; -.
DR Proteomes; UP000000589; Chromosome 4.
DR RNAct; Q3V036; protein.
DR Bgee; ENSMUSG00000039492; Expressed in spermatid and 23 other tissues.
DR ExpressionAtlas; Q3V036; baseline and differential.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..639
FT /note="Coiled-coil domain-containing protein 27"
FT /id="PRO_0000234021"
FT REGION 154..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 203..242
FT /evidence="ECO:0000255"
FT COMPBIAS 160..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..354
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 73651 MW; B3F525B3C5936206 CRC64;
MKQENLTQEC CSTSPKISKG LMVLQSIASR GCDTQDSEKK PQSTQQSLKK SSQAAAGYFY
DKEDQIRKLS KHNGFLSEME DMRKAFLMRP GCPQFSTRTT SMSHVGSAIM VDLPRTCSGV
WKLTEDHPLG RLGSASSVDG RVFPFSKSAC ELNYPRKRSE PSDPSPTGSP TVVKKSQRTR
TPWYISVIHE KDHSLLLMGE ELQRFSEMES QMQKKDQEIL TLQKEKEALK KQLKNLLRGK
GTETSSASIK MDRSFETPLK LGRMSVLKTI YKEEDELQHW MQMQEEYSMA ESSKELHVEP
GSAIEEKSSE GPPEEAAAAK LSRPSQSKTE TLLEVGPEEE EEEEEEEVEG DEAKGTEEGE
ILVNEEEASW ELREDEECHP KRSYSMTESF EEELMAQLEE YERMLMDFQR ELEFTRSRYS
LATGTITSLQ RQTDFQESQL RKVTTENELL EKELRERKQQ IQDMTDKFSN LREEKKHQEI
MGLIEKENLV LRQQVADLKM DLISSERTIK ELNTQTKELE DQVNTDKDHL RRWKDLHDDL
QTRNEIIQQT EQQTRVVLEA TQARYEKLRN KIIQAVFSVS GNKNLSMELS DSYILESLQR
IISERSDFYS QLKQKGVKVP PLQQSDVSLP SKIKKMASK