ID   CCD30_MACFA             Reviewed;         743 AA.
AC   Q8WP33; Q95JV8; Q95LV2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Coiled-coil domain-containing protein 30;
DE   AltName: Full=Prefoldin subunit 6-like protein;
GN   Name=CCDC30; Synonyms=PFDN6L; ORFNames=QtsA-10590, QtsA-16296, QtsA-17713;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3).
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q8WP33-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8WP33-2; Sequence=VSP_033796, VSP_033797;
CC       Name=3;
CC         IsoId=Q8WP33-3; Sequence=VSP_033793, VSP_033794, VSP_033795;
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB070070; BAB63015.1; -; mRNA.
DR   EMBL; AB071089; BAB64483.1; -; mRNA.
DR   EMBL; AB074444; BAB72075.1; -; mRNA.
DR   AlphaFoldDB; Q8WP33; -.
DR   SMR; Q8WP33; -.
DR   PRIDE; Q8WP33; -.
DR   eggNOG; ENOG502SNA5; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   InterPro; IPR031476; DUF4686.
DR   Pfam; PF15742; DUF4686; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Coiled coil; Reference proteome.
FT   CHAIN           1..743
FT                   /note="Coiled-coil domain-containing protein 30"
FT                   /id="PRO_0000336045"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          114..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          208..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          21..98
FT                   /evidence="ECO:0000255"
FT   COILED          165..580
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        121..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         38
FT                   /note="S -> SESHGLISRFNPLSCHLGKIYQEIQSAYILKRDL (in isoform
FT                   3)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_033793"
FT   VAR_SEQ         347..350
FT                   /note="SKVA -> MKLK (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_033794"
FT   VAR_SEQ         351..743
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_033795"
FT   VAR_SEQ         547..578
FT                   /note="KAIQDQITAQNDTLLLEKRKLQEQVIEQEQLI -> EEGKTHRQTQTGEECL
FT                   MMMKSETGMIQLQAKK (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_033796"
FT   VAR_SEQ         579..743
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12498619"
FT                   /id="VSP_033797"
FT   CONFLICT        156
FT                   /note="E -> G (in Ref. 1; BAB63015)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   743 AA;  86465 MW;  4DF10EBB85E0FD36 CRC64;
     MSQEKNEMFE SEWSKERERE KQLASGLDTA EKALKAESEE LQKSKSELIC LYNEVHNLPG
     ASESRDHFLI ACDLLRRENS ELETKVLKLS QEFAQLNHFT LRGKTAPSNL ITSENICKDP
     ESNEPVLEIE IQSPKEEREE LCPKLGERKQ KEIPEESVKE GSFPREGQKE EGSQQNQDMK
     DEEKEQRLTM KPEEVVRLRE ELSRINQSLL QSQSSGDSSD DSGAQYPSSG DKLKYNQQGE
     VQQLHQNLHR LQILCNSAEN ELRYERGKNL DLKQHNSLLQ EENIKIKIEL KHAQQKLLES
     TKMCSSLTAE CKQSQQKIKE LELEVLKQTQ SIKSQNNLQE KLAQEKSKVA DAEEKILDLQ
     RKLEHAHKVC LTDTCISEKQ QLEEKIKEAT ENEAKVKQQY QEEQQKRKLL YQNTDELHRQ
     VRTLQDKENL LEMTCSQQQS RIQQQEALLK QLENEKRKYD EDVKSNQELS EKLSKLQQEK
     EALREEYLRL LKLLNVHVRN YNEKHQQHKI KLQKVKYRLT NEVELRDKRI NEFEDEIGIL
     QHKIEKKAIQ DQITAQNDTL LLEKRKLQEQ VIEQEQLIHS NKWTISSIQS RVLYMDKENK
     QLQEISLRLP ATKKQKEIYS TEVCTCNNAE LQHEDESVPK ATEKWKHSEQ METTISDILE
     SEVVNEILPL SNSSFSGKGL VESFVSLQET DDIKSKEAMA SSKSPEKSPE NLVCSQNSEA
     GYINVTSLKE THGIQEQDQK SEL