CCD32_ARATH
ID CCD32_ARATH Reviewed; 367 AA.
AC Q9FGQ7;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 140.
DE RecName: Full=Cyclin-D3-2;
DE AltName: Full=G1/S-specific cyclin-D3-2;
DE Short=CycD3;2;
GN Name=CYCD3-2; OrderedLocusNames=At5g67260; ORFNames=K3G17.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=11115883; DOI=10.1104/pp.124.4.1658;
RA Swaminathan K., Yang Y., Grotz N., Campisi L., Jack T.;
RT "An enhancer trap line associated with a D-class cyclin gene in
RT Arabidopsis.";
RL Plant Physiol. 124:1658-1667(2000).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
RN [7]
RP FUNCTION, AND INTERACTION WITH CDKA-1.
RC STRAIN=cv. Columbia;
RX PubMed=24687979; DOI=10.1093/jxb/eru139;
RA Yang K., Wang H., Xue S., Qu X., Zou J., Le J.;
RT "Requirement for A-type cyclin-dependent kinase and cyclins for the
RT terminal division in the stomatal lineage of Arabidopsis.";
RL J. Exp. Bot. 65:2449-2461(2014).
CC -!- FUNCTION: Promotes divisions in the guard cells (GCs) after the guard
CC mother cells (GMC) symmetric division when in the presence of CDKA-1.
CC {ECO:0000269|PubMed:24687979}.
CC -!- SUBUNIT: Interacts with CDKA-1. {ECO:0000269|PubMed:24687979}.
CC -!- TISSUE SPECIFICITY: Expressed in developing vegetative and floral
CC primordia. {ECO:0000269|PubMed:11115883}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin D subfamily.
CC {ECO:0000305}.
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DR EMBL; AB025614; BAB09645.1; -; Genomic_DNA.
DR EMBL; CP002688; AED98321.1; -; Genomic_DNA.
DR EMBL; AY062645; AAL32723.1; -; mRNA.
DR EMBL; AY093254; AAM13253.1; -; mRNA.
DR EMBL; AY087540; AAM65082.1; -; mRNA.
DR RefSeq; NP_201527.1; NM_126126.3.
DR AlphaFoldDB; Q9FGQ7; -.
DR SMR; Q9FGQ7; -.
DR BioGRID; 22103; 20.
DR IntAct; Q9FGQ7; 10.
DR STRING; 3702.AT5G67260.1; -.
DR iPTMnet; Q9FGQ7; -.
DR PaxDb; Q9FGQ7; -.
DR DNASU; 836861; -.
DR EnsemblPlants; AT5G67260.1; AT5G67260.1; AT5G67260.
DR GeneID; 836861; -.
DR Gramene; AT5G67260.1; AT5G67260.1; AT5G67260.
DR KEGG; ath:AT5G67260; -.
DR Araport; AT5G67260; -.
DR TAIR; locus:2157172; AT5G67260.
DR eggNOG; KOG0656; Eukaryota.
DR HOGENOM; CLU_048040_0_0_1; -.
DR InParanoid; Q9FGQ7; -.
DR OMA; DHIMRRF; -.
DR PhylomeDB; Q9FGQ7; -.
DR PRO; PR:Q9FGQ7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGQ7; baseline and differential.
DR Genevisible; Q9FGQ7; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0010444; P:guard mother cell differentiation; IMP:UniProtKB.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:1901371; P:regulation of leaf morphogenesis; IMP:TAIR.
DR GO; GO:0048316; P:seed development; IGI:TAIR.
DR CDD; cd00043; CYCLIN; 1.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..367
FT /note="Cyclin-D3-2"
FT /id="PRO_0000287025"
FT REGION 324..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 42351 MW; 9D26B28A66152C54 CRC64;
MALEKEEEAS QNGAFCVLDG LYCEEETGFV EDDLDDDGDL DFLEKSDESV VKFQFLPLLD
MFLWDDDEIL SLISKENETN PCFGEQILDG FLVSCRKEAL DWVLRVKSHY GFTSLTAILA
VNYFDRFMTS IKLQTDKPWM SQLVAVASLS LAAKVEEIQV PLLLDLQVEE ARYLFEAKTI
QRMELLILST LQWRMHPVTP ISFFDHIIRR FGSKWHQQLD FCRKCERLLI SVIADTRFMR
YFPSVLATAI MILVFEELKP CDEVEYQSQI TTLLKVNQEK VNECYELLLE HNPSKKRMMN
LVDQDSPSGV LDFDDSSNSS WNVSTTASVS SSSSSPEPLL KRRRVQEQQM RLPSINRMFL
DVLSSPR
