CCD34_MOUSE
ID CCD34_MOUSE Reviewed; 367 AA.
AC Q3UI66; Q9CS29; Q9CS41;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Coiled-coil domain-containing protein 34;
GN Name=Ccdc34;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Amnion, and Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AK019172; BAB31586.1; -; mRNA.
DR EMBL; AK019247; BAB31625.1; -; mRNA.
DR EMBL; AK147056; BAE27640.1; -; mRNA.
DR EMBL; AL928922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS50655.1; -.
DR RefSeq; NP_080889.3; NM_026613.4.
DR AlphaFoldDB; Q3UI66; -.
DR STRING; 10090.ENSMUSP00000028580; -.
DR PhosphoSitePlus; Q3UI66; -.
DR MaxQB; Q3UI66; -.
DR PaxDb; Q3UI66; -.
DR PRIDE; Q3UI66; -.
DR Antibodypedia; 48802; 68 antibodies from 13 providers.
DR Ensembl; ENSMUST00000028580; ENSMUSP00000028580; ENSMUSG00000027160.
DR GeneID; 68201; -.
DR KEGG; mmu:68201; -.
DR UCSC; uc008lmr.2; mouse.
DR CTD; 91057; -.
DR MGI; MGI:1915451; Ccdc34.
DR VEuPathDB; HostDB:ENSMUSG00000027160; -.
DR eggNOG; ENOG502RRPQ; Eukaryota.
DR GeneTree; ENSGT00730000111271; -.
DR HOGENOM; CLU_063061_0_0_1; -.
DR InParanoid; Q3UI66; -.
DR OMA; FTGDCRP; -.
DR OrthoDB; 1618244at2759; -.
DR PhylomeDB; Q3UI66; -.
DR TreeFam; TF333383; -.
DR BioGRID-ORCS; 68201; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Ccdc34; mouse.
DR PRO; PR:Q3UI66; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q3UI66; protein.
DR Bgee; ENSMUSG00000027160; Expressed in dorsal pancreas and 209 other tissues.
DR ExpressionAtlas; Q3UI66; baseline and differential.
DR Genevisible; Q3UI66; MM.
DR InterPro; IPR045323; CCDC34.
DR InterPro; IPR025259; CCDC34/181.
DR PANTHER; PTHR23247; PTHR23247; 1.
DR Pfam; PF13904; DUF4207; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..367
FT /note="Coiled-coil domain-containing protein 34"
FT /id="PRO_0000339112"
FT REGION 77..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 87..108
FT /evidence="ECO:0000255"
FT COILED 153..280
FT /evidence="ECO:0000255"
FT COMPBIAS 310..324
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 55
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96HJ3"
SQ SEQUENCE 367 AA; 42216 MW; 248EA9A4D522BB56 CRC64;
MRAAGPWRAA SPAPCTRYLA RCKPGFRPSS SFVVDLLVDS GDPGLEDVAL TECLSPPSLS
CSNSTLSLLS PLGHQSFPFG ADDSEGEDEE ALDEDARESE SKVESLEGIE FQQRSSCEVE
SQDKQEKLVL LQHGSLTPWE MWFVGKEKEE RGRLQQKFLE ELNQQIEKRK EMEEREKRKI
IAEVKHKEWV QKKNKQERKE REQKINKEME EKEAKKREKE HLQEKAKEKY QEWLKKKKAE
EYEKKKKEKE KEKQRQAELQ EKKEIAEKKF KEWLENAKNK PRPAAKSYGY SSGKLTGFYS
GNSYPEPTFY NPIPWKPIHM PPPKEAKSGP GKKSKRHAAS QPLPSSSLAV HNAKSSLCLG
ALCRGQR
