CCD38_MACFA
ID CCD38_MACFA Reviewed; 563 AA.
AC Q95JL6; Q95JQ7;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Coiled-coil domain-containing protein 38;
GN Name=CCDC38; ORFNames=QtsA-14402, QtsA-15696;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA Terao K., Sugano S., Hashimoto K.;
RT "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT the human genome sequence.";
RL BMC Genomics 3:36-36(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Testis;
RA Hashimoto K., Osada N., Hida M., Kusuda J., Tanuma R., Hirai M., Terao K.,
RA Sugano S.;
RT "Isolation of novel full-length cDNA clones from macaque testis cDNA
RT libraries.";
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250|UniProtKB:Q502W7}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q95JL6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q95JL6-2; Sequence=VSP_018329, VSP_018330;
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DR EMBL; AB070122; BAB63067.1; -; mRNA.
DR EMBL; AB070165; BAB63110.1; -; mRNA.
DR AlphaFoldDB; Q95JL6; -.
DR SMR; Q95JL6; -.
DR STRING; 9541.XP_005571963.1; -.
DR eggNOG; ENOG502QSDI; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR025252; DUF4200.
DR Pfam; PF13863; DUF4200; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Cytoplasm; Cytoskeleton;
KW Reference proteome.
FT CHAIN 1..563
FT /note="Coiled-coil domain-containing protein 38"
FT /id="PRO_0000234491"
FT REGION 521..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 129..212
FT /evidence="ECO:0000255"
FT COILED 384..415
FT /evidence="ECO:0000255"
FT COILED 485..522
FT /evidence="ECO:0000255"
FT VAR_SEQ 305..307
FT /note="KSN -> LKR (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_018329"
FT VAR_SEQ 398..563
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_018330"
SQ SEQUENCE 563 AA; 65655 MW; 5A1210F6517416CA CRC64;
MSSNLSPTLN SGDKVKDGSI KEDRPYKIFF RDLFLFKENE MEAKKTEKLM NHNMKVYQKT
TFSSRMKSRS YLSQLAFYPK RGGRSFEKFG PGPAPISRFL EGSDTKRTVH EFINDQRDRF
LLEYALSTKR NTIKKFEKDI AMRERQLKKA EKKLQDDALA FEEFLRENDQ RSVDALKLAA
QETINKLQMT AELKKASMEV QAVKSEIAKT EFLLKEYMKY GFFLLQLSPK HWQIQQALKR
AQASKSKANI ILPKILARLS LHSSKKEGIL EEFGGTAILS EDASRERDSQ GKPSRILTRT
SEKIKSNLTE SFGSEDSLEF LLDDEMDFDL EPALYFKEPE ELLQVLRELE EQNLTLFQYS
QDVDENLEEV NKREKVIQDK TNSNIEFLLE QEEMLKANCV REEEKAAELQ LRSRLFSFGE
FNSDAQEILI DSLSKKITEV YKVCIGDAED DGLNPIQKLV KVESRLVELC DLIESIPREN
VEAIERMKQK ERRQKFRDEK MREKQRHQEE RLKAALEKAV AQPKKKLGRR LVYHSKPPSA
NKQQLPLVNE TKTKAQEEEY FFT