ID   CCD50_CHICK             Reviewed;         301 AA.
AC   Q5ZM86;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Coiled-coil domain-containing protein 50;
GN   Name=CCDC50; ORFNames=RCJMB04_2n23;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Involved in EGFR signaling. {ECO:0000250}.
CC   -!- PTM: Phosphorylated on tyrosine residues. {ECO:0000250}.
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DR   EMBL; AJ719498; CAG31157.1; -; mRNA.
DR   RefSeq; NP_001026486.1; NM_001031315.1.
DR   AlphaFoldDB; Q5ZM86; -.
DR   SMR; Q5ZM86; -.
DR   STRING; 9031.ENSGALP00000032727; -.
DR   PRIDE; Q5ZM86; -.
DR   GeneID; 424906; -.
DR   KEGG; gga:424906; -.
DR   CTD; 152137; -.
DR   VEuPathDB; HostDB:geneid_424906; -.
DR   eggNOG; ENOG502S0GI; Eukaryota.
DR   InParanoid; Q5ZM86; -.
DR   OrthoDB; 1110962at2759; -.
DR   PhylomeDB; Q5ZM86; -.
DR   PRO; PR:Q5ZM86; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   InterPro; IPR039303; CCDC50.
DR   InterPro; IPR029311; CCDC50_N.
DR   PANTHER; PTHR22115; PTHR22115; 2.
DR   Pfam; PF15295; CCDC50_N; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..301
FT                   /note="Coiled-coil domain-containing protein 50"
FT                   /id="PRO_0000066306"
FT   REGION          123..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          214..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          57..131
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        123..144
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        159..175
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..270
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   301 AA;  35499 MW;  58B69D6A6730F4FB CRC64;
     MAEIGIDQSK LPGVKEVCRD FAVLEDHTLA HNLQEQEIEH HLATNIQRNR LVQHDLQVAK
     QLQEEEDLKA RAQIQKRQKD LERQDSEIAQ EIQVKLVFEA EQRRRQEEKD EDIARLLQQK
     ELQEEKKRKK HYPESQEHKV YEDSYYSENG GTKLRGTKQT VYDKPRREQE LSDAEIARKL
     QEEELLANQA DQMAAQVAQD EEIARLLMAE EKKAFKKGKE KEKSSFERKR NDQDWKHDAS
     ESPRSRSKEG PETQRHKGDK SSRSQPLLDD FEHARYYTSQ PSPLRQFSKP EHSPKGSRRK
     Q