CCD54_MOUSE
ID CCD54_MOUSE Reviewed; 329 AA.
AC Q9DAL3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Coiled-coil domain-containing protein 54;
GN Name=Ccdc54;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK005741; BAB24216.1; -; mRNA.
DR EMBL; BC049741; AAH49741.1; -; mRNA.
DR CCDS; CCDS28214.1; -.
DR RefSeq; NP_081322.1; NM_027046.3.
DR AlphaFoldDB; Q9DAL3; -.
DR SMR; Q9DAL3; -.
DR STRING; 10090.ENSMUSP00000049864; -.
DR iPTMnet; Q9DAL3; -.
DR PhosphoSitePlus; Q9DAL3; -.
DR PaxDb; Q9DAL3; -.
DR PRIDE; Q9DAL3; -.
DR ProteomicsDB; 265365; -.
DR Antibodypedia; 46519; 150 antibodies from 17 providers.
DR DNASU; 69339; -.
DR Ensembl; ENSMUST00000062439; ENSMUSP00000049864; ENSMUSG00000050685.
DR GeneID; 69339; -.
DR KEGG; mmu:69339; -.
DR UCSC; uc007zkx.1; mouse.
DR CTD; 84692; -.
DR MGI; MGI:1916589; Ccdc54.
DR VEuPathDB; HostDB:ENSMUSG00000050685; -.
DR eggNOG; ENOG502SSGK; Eukaryota.
DR GeneTree; ENSGT00390000008948; -.
DR HOGENOM; CLU_074373_0_0_1; -.
DR InParanoid; Q9DAL3; -.
DR OMA; LENQNSC; -.
DR OrthoDB; 1013973at2759; -.
DR PhylomeDB; Q9DAL3; -.
DR TreeFam; TF338361; -.
DR BioGRID-ORCS; 69339; 5 hits in 70 CRISPR screens.
DR ChiTaRS; Ccdc54; mouse.
DR PRO; PR:Q9DAL3; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; Q9DAL3; protein.
DR Bgee; ENSMUSG00000050685; Expressed in seminiferous tubule of testis and 6 other tissues.
DR Genevisible; Q9DAL3; MM.
DR InterPro; IPR037758; Ccdc54.
DR PANTHER; PTHR37880; PTHR37880; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..329
FT /note="Coiled-coil domain-containing protein 54"
FT /id="PRO_0000286670"
FT REGION 178..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 86..149
FT /evidence="ECO:0000255"
FT COMPBIAS 178..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 182
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q8NEL0"
SQ SEQUENCE 329 AA; 37518 MW; 202CB6065262D75A CRC64;
MYRFHTKRVR AAAGQVWTAN LHKIRRSLKN VYQKCTTHHS YSTSYPTRAS YGCDGDTLSL
NEDMNLPAML QDIKTGQTEL LNQMTNIVSS ISNIQEKINH YQNQMEALEA RINISEDRQT
ATTKDMLSMK EDINTLKKKV TELESQNSYS SIHCLEVLEG QRGKEFVQLL HKLLQTETPK
GTATSPDTVI SSAEPERVSS YPEPTGELKK KTTSPQNITL KKNNSLQNAS VGCKKVRSNI
YIYPDFSTWI KLTFVHGGNW RFFLSATKLE EFIQWLLSRS TILPEEPQII PQRDYAFTGA
IGRLATICLS LFHYVYCLFG SSKEEITRL