ID   CCD63_BOVIN             Reviewed;         558 AA.
AC   Q2T9W3;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Coiled-coil domain-containing protein 63 {ECO:0000250|UniProtKB:Q8NA47};
GN   Name=CCDC63 {ECO:0000250|UniProtKB:Q8NA47};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in spermiogenesis. Involved in the elongation of
CC       flagella and the formation of sperm heads.
CC       {ECO:0000250|UniProtKB:Q8CDV6}.
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DR   EMBL; BC111238; AAI11239.1; -; mRNA.
DR   RefSeq; NP_001069231.1; NM_001075763.2.
DR   AlphaFoldDB; Q2T9W3; -.
DR   SMR; Q2T9W3; -.
DR   STRING; 9913.ENSBTAP00000043247; -.
DR   PaxDb; Q2T9W3; -.
DR   PRIDE; Q2T9W3; -.
DR   Ensembl; ENSBTAT00000045892; ENSBTAP00000043247; ENSBTAG00000032353.
DR   GeneID; 518001; -.
DR   KEGG; bta:518001; -.
DR   CTD; 160762; -.
DR   VEuPathDB; HostDB:ENSBTAG00000032353; -.
DR   VGNC; VGNC:26907; CCDC63.
DR   eggNOG; ENOG502QSIU; Eukaryota.
DR   GeneTree; ENSGT00940000153116; -.
DR   HOGENOM; CLU_027546_2_0_1; -.
DR   InParanoid; Q2T9W3; -.
DR   OMA; QRCLLMQ; -.
DR   OrthoDB; 648380at2759; -.
DR   TreeFam; TF323742; -.
DR   Proteomes; UP000009136; Chromosome 17.
DR   Bgee; ENSBTAG00000032353; Expressed in spermatid and 17 other tissues.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR   GO; GO:0036158; P:outer dynein arm assembly; IBA:GO_Central.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Coiled coil; Differentiation; Reference proteome; Spermatogenesis.
FT   CHAIN           1..558
FT                   /note="Coiled-coil domain-containing protein 63"
FT                   /id="PRO_0000288873"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..558
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          48..289
FT                   /evidence="ECO:0000255"
FT   COILED          339..416
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        534..558
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   558 AA;  65966 MW;  7C3CB80C0CBCCF4E CRC64;
     MPTKKHRRKD PESPQEPSEK TKEQLVEGEL RKLRQQFRKM VDSRKSFNFR SQQKITNQRK
     EIKTLQEEQD EITLLLNLIK SSRNLDLNEK NYLELRFLLQ TKEDYEALIK SMKLLLAELD
     EKIVQMEKKI INQRQIFTKI QEANNPRKLQ KQIHILETRL NLVTVHFDQM LTTNAKLRKE
     IEDLRHEKAA YDNVYQHLRR RLLTKKKTMN VAIEQSAQAY EQRLEAMARM AAMKDRQQKD
     ISQYNLEIRE LERVYDHETK LKSFLLIKLN DRLEFEEQSK KEEALKAKKY GKKSKGASFE
     SYEVAHLRLL KLTKTGNLNQ LIEEFLAKEE KNFARFTYVT ELNNDMEMMH KKIERIQNEI
     LRLRSQQKSS HDDSYSILRE LEEKLKKTTE EADMYENDYR EITKTLEYLK NSVENLFKKI
     NCDATKILVQ LGETGKVTDI NLPQYFAIIE KKTNDLLVLE SYKRLMEMEV AEAEVQPSFL
     NPFWGGSALL KPAEPIKVIP PVLGADPLSD KLDEVEQPLD HSSLRQMVLS HYATRESRNR
     DSMPEKGDEL KSKKKVTV