ID   CCD63_RAT               Reviewed;         559 AA.
AC   Q4V8F7;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Coiled-coil domain-containing protein 63 {ECO:0000312|RGD:1562334};
GN   Name=Ccdc63 {ECO:0000312|RGD:1562334};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Plays a role in spermiogenesis. Involved in the elongation of
CC       flagella and the formation of sperm heads.
CC       {ECO:0000250|UniProtKB:Q8CDV6}.
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DR   EMBL; BC097409; AAH97409.1; -; mRNA.
DR   RefSeq; NP_001020836.1; NM_001025665.1.
DR   AlphaFoldDB; Q4V8F7; -.
DR   SMR; Q4V8F7; -.
DR   STRING; 10116.ENSRNOP00000043589; -.
DR   PhosphoSitePlus; Q4V8F7; -.
DR   Ensembl; ENSRNOT00000046604; ENSRNOP00000043589; ENSRNOG00000034266.
DR   GeneID; 304484; -.
DR   KEGG; rno:304484; -.
DR   UCSC; RGD:1562334; rat.
DR   CTD; 160762; -.
DR   RGD; 1562334; Ccdc63.
DR   GeneTree; ENSGT00940000153116; -.
DR   InParanoid; Q4V8F7; -.
DR   OrthoDB; 648380at2759; -.
DR   PhylomeDB; Q4V8F7; -.
DR   PRO; PR:Q4V8F7; -.
DR   Proteomes; UP000002494; Chromosome 12.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR   GO; GO:0036158; P:outer dynein arm assembly; IBA:GO_Central.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR   InterPro; IPR029652; CCDC63_fam.
DR   PANTHER; PTHR21694:SF18; PTHR21694:SF18; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Differentiation; Reference proteome; Spermatogenesis.
FT   CHAIN           1..559
FT                   /note="Coiled-coil domain-containing protein 63"
FT                   /id="PRO_0000288876"
FT   COILED          14..70
FT                   /evidence="ECO:0000255"
FT   COILED          185..261
FT                   /evidence="ECO:0000255"
FT   COILED          364..414
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   559 AA;  66107 MW;  8E51210D0D9167E6 CRC64;
     MKKHRRKVSE PLPELSEKAK EQLAEAELRK LRQQFRKMVD SRKSSNFRNQ RMIASQYKEI
     ENLKAEQAET TLLLSLVKSP KNLDLNQKNF TELRFLLQTK GDYEALISSM KVLLGELDDK
     IVQMERKITN QRQIFLKTQE ANNPRKLQKQ IHILETRLNL VTVHFDTMLT SNAQLRKDIE
     DLLFEKAAYD HVYQQLQRRL QTQKKTMNVA IEQSTQAYEQ RVEAMARMAA MKDRQQKDIS
     QYNLEIRELE RLYDHENKLK SFLLVKLNDR TEFEDQAKKQ EAVKIKKHGK KRKGESFESY
     EVAHLRLLKL AENGDLNQLT EDFLAKEEKN FARFTYVTEL NNDMETMHKR TQRIQDDIIN
     LRSQQQSSHE GTRNILKQME EKLRKTTEDT DIYENRYREM SKTLEYLKNS VEKLFKKINC
     NATEILGKLG ETGKITDSNL QQYFAIIEKK TNDLLLLESF RRLQEAEGPD VDVPQPFVNP
     FWGGSALLKP PEPLRVVPPV FGADSFSDKV EEVPHRALSW VQWNTLWTTV ASGSWSWRTT
     FRRNEEKNHR RHCWRRGTR