ID   CCD69_XENTR             Reviewed;         305 AA.
AC   Q0IHN7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Coiled-coil domain-containing protein 69;
GN   Name=ccdc69;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Fat body;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a scaffold to regulate the recruitment and
CC       assembly of spindle midzone components. {ECO:0000250|UniProtKB:A6NI79}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000250|UniProtKB:A6NI79}. Midbody {ECO:0000250|UniProtKB:A6NI79}.
CC       Note=During early anaphase, localizes along overlapping interpolar
CC       microtubules between the separating chromosomes. During late anaphase,
CC       localizes to the center of spindle midzone. Concentrated at the midbody
CC       during telophase. {ECO:0000250|UniProtKB:A6NI79}.
CC   -!- SIMILARITY: Belongs to the CCDC69 family. {ECO:0000305}.
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DR   EMBL; BC123063; AAI23064.1; -; mRNA.
DR   RefSeq; NP_001072629.1; NM_001079161.1.
DR   AlphaFoldDB; Q0IHN7; -.
DR   SMR; Q0IHN7; -.
DR   STRING; 8364.ENSXETP00000042070; -.
DR   PaxDb; Q0IHN7; -.
DR   DNASU; 780085; -.
DR   Ensembl; ENSXETT00000042070; ENSXETP00000042070; ENSXETG00000019409.
DR   GeneID; 780085; -.
DR   KEGG; xtr:780085; -.
DR   CTD; 26112; -.
DR   eggNOG; ENOG502RYPP; Eukaryota.
DR   HOGENOM; CLU_079661_0_0_1; -.
DR   InParanoid; Q0IHN7; -.
DR   OMA; TMERNLV; -.
DR   OrthoDB; 1278490at2759; -.
DR   PhylomeDB; Q0IHN7; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000019409; Expressed in heart and 13 other tissues.
DR   ExpressionAtlas; Q0IHN7; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0051233; C:spindle midzone; ISS:UniProtKB.
DR   GO; GO:0051255; P:spindle midzone assembly; ISS:UniProtKB.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Lipoprotein; Myristate;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..305
FT                   /note="Coiled-coil domain-containing protein 69"
FT                   /id="PRO_0000328967"
FT   REGION          13..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          42..167
FT                   /evidence="ECO:0000255"
FT   COILED          216..278
FT                   /evidence="ECO:0000255"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   305 AA;  35538 MW;  8B3ABA6BBBA5AF22 CRC64;
     MGCKTSKMCC PRLRKKKRQK AHQEGLTSKE LNDLNAKSQE PNELLQKIKK YEQETRDILQ
     KHQAEKAALA DTHKADVEAR TLELQAQAQK DRDADIAKLL LEQAATIKVE MEEKLAELQK
     SNEQEKASLT ETHQQLIDSL QERVDELKTQ LASFQEKMKR VEESVLSQDY RRHIQDHGSP
     GQFWEQEIQS LHFVIEMKSE LIREQDKRLR SHKSTMERNL VLEERSRTLQ QENEALKVQT
     QKQGAVTVRL SEELLSTQAT LEKQIHLREK LEREKEQNLY RAVNGDIPQQ FSLQSNAQEL
     PVMVL