CCD71_MOUSE
ID CCD71_MOUSE Reviewed; 433 AA.
AC Q8VEG0; Q3UDX1;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Coiled-coil domain-containing protein 71;
GN Name=Ccdc71;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, Head, Retina, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK044601; BAC31997.1; -; mRNA.
DR EMBL; AK086560; BAC39691.1; -; mRNA.
DR EMBL; AK149878; BAE29140.1; -; mRNA.
DR EMBL; AK161396; BAE36372.1; -; mRNA.
DR EMBL; BC018518; AAH18518.1; -; mRNA.
DR CCDS; CCDS23527.1; -.
DR RefSeq; NP_598505.1; NM_133744.4.
DR RefSeq; XP_006511900.1; XM_006511837.3.
DR AlphaFoldDB; Q8VEG0; -.
DR SMR; Q8VEG0; -.
DR STRING; 10090.ENSMUSP00000057891; -.
DR iPTMnet; Q8VEG0; -.
DR PhosphoSitePlus; Q8VEG0; -.
DR EPD; Q8VEG0; -.
DR jPOST; Q8VEG0; -.
DR MaxQB; Q8VEG0; -.
DR PaxDb; Q8VEG0; -.
DR PRIDE; Q8VEG0; -.
DR ProteomicsDB; 281315; -.
DR Antibodypedia; 56320; 68 antibodies from 15 providers.
DR DNASU; 72454; -.
DR Ensembl; ENSMUST00000061209; ENSMUSP00000057891; ENSMUSG00000049305.
DR Ensembl; ENSMUST00000193170; ENSMUSP00000142230; ENSMUSG00000049305.
DR GeneID; 72454; -.
DR KEGG; mmu:72454; -.
DR UCSC; uc009rpq.2; mouse.
DR CTD; 64925; -.
DR MGI; MGI:1919704; Ccdc71.
DR VEuPathDB; HostDB:ENSMUSG00000049305; -.
DR eggNOG; ENOG502RY9H; Eukaryota.
DR GeneTree; ENSGT00940000155306; -.
DR HOGENOM; CLU_049410_1_0_1; -.
DR InParanoid; Q8VEG0; -.
DR OMA; EWKDSST; -.
DR OrthoDB; 802843at2759; -.
DR PhylomeDB; Q8VEG0; -.
DR TreeFam; TF336191; -.
DR BioGRID-ORCS; 72454; 3 hits in 73 CRISPR screens.
DR ChiTaRS; Ccdc71; mouse.
DR PRO; PR:Q8VEG0; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q8VEG0; protein.
DR Bgee; ENSMUSG00000049305; Expressed in embryonic brain and 244 other tissues.
DR ExpressionAtlas; Q8VEG0; baseline and differential.
DR Genevisible; Q8VEG0; MM.
DR InterPro; IPR026695; Ccdc71/71L.
DR PANTHER; PTHR14484; PTHR14484; 1.
DR Pfam; PF15374; CCDC71L; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..433
FT /note="Coiled-coil domain-containing protein 71"
FT /id="PRO_0000234422"
FT REGION 204..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 260..330
FT /evidence="ECO:0000255"
FT COMPBIAS 351..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 125
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8IV32"
FT CONFLICT 312
FT /note="R -> W (in Ref. 1; BAE29140)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 433 AA; 46010 MW; 0DB9C0883F256315 CRC64;
MSMVVQPVEE KAVHSWSRIS TAGKKALEEA LLVFNPMSQD LSATEAQLVA FLQGLRDDGF
QPTILRSGDV YGYSSCTASP PSQTKLQART INPPATSLPK TAVSVPAGRT TLLPVPLSGR
LAKGSTAALA KHATTNLLLS SLKQSSASNS SGTTVGFPAH LYPGVYPAMR LSVVLEALVP
LKTPCLDVKH GAQSLQLSLA KSPLKVRKAS GNPKSKAPRK ITSKGLKHLT SKGPGAGLRR
GAGTQSNGAQ RKGCSALGPK TVQAQASQTL IKAARAHASV AQTQTKTVRV RAKAKQAKPK
AARAKAKAAV VRDKAKDKVI QAKAKAAQTK HKGKPKGSVQ TRTGRANRKN SSETVGRKRK
KAEETKGLPP KKRARCVPRP PKVWLGPGTA KPRKSQTIKV DRKCSDDEVR QCAQQILRVN
LSPVVWLQPL LPF
