ID   CCD89_DANRE             Reviewed;         354 AA.
AC   A8WG43;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Coiled-coil domain-containing protein 89 {ECO:0000250|UniProtKB:Q8N998};
DE   AltName: Full=Bc8 orange-interacting protein {ECO:0000303|PubMed:14648848};
GN   Name=ccdc89 {ECO:0000250|UniProtKB:Q8N998};
GN   Synonyms=boip {ECO:0000303|PubMed:14648848}; ORFNames=zgc:172182;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1] {ECO:0000312|EMBL:AAI54574.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis {ECO:0000312|EMBL:AAI54574.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=14648848; DOI=10.1002/dvdy.10406;
RA   Van Wayenbergh R., Taelman V., Pichon B., Fischer A., Kricha S.,
RA   Gessler M., Christophe D., Bellefroid E.J.;
RT   "Identification of BOIP, a novel cDNA highly expressed during
RT   spermatogenesis that encodes a protein interacting with the orange domain
RT   of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse.";
RL   Dev. Dyn. 228:716-725(2003).
CC   -!- SUBUNIT: Interacts with hey1. {ECO:0000250|UniProtKB:Q7ZW57}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q7ZW57}. Nucleus
CC       {ECO:0000250|UniProtKB:Q7ZW57}. Note=Uniformly distributed within the
CC       cell, but becomes recruited to the nucleus upon binding to hey1.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCDC89 family. {ECO:0000255}.
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DR   EMBL; BC154573; AAI54574.1; -; mRNA.
DR   RefSeq; NP_001108038.1; NM_001114566.1.
DR   AlphaFoldDB; A8WG43; -.
DR   SMR; A8WG43; -.
DR   STRING; 7955.ENSDARP00000058247; -.
DR   PaxDb; A8WG43; -.
DR   GeneID; 100136847; -.
DR   KEGG; dre:100136847; -.
DR   ZFIN; ZDB-GENE-080204-56; zgc:172182.
DR   eggNOG; ENOG502QU10; Eukaryota.
DR   InParanoid; A8WG43; -.
DR   OrthoDB; 1122259at2759; -.
DR   PhylomeDB; A8WG43; -.
DR   PRO; PR:A8WG43; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR043450; CCDC89-like.
DR   PANTHER; PTHR34768; PTHR34768; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..354
FT                   /note="Coiled-coil domain-containing protein 89"
FT                   /id="PRO_0000370203"
FT   COILED          10..334
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   354 AA;  42156 MW;  A29F3C89CC17F693 CRC64;
     MTSPQKIPID LKMMIKDTKQ DMDDVHQALE KLRSLSQEER TEAEVLRSRI DEQSTLICIL
     KRRADEMLLR CQALEKINAE LENLRANVQV ELENERKKSE LLEQRFMDLA SNHRELINFK
     NEYKSQNAKL EKENERLRKE NEALFSEEVQ EKEETILKLT QELKDLAEQH KILENEYQEK
     TTGFQIKLKE LMNLHRIKEA SLKNELSDTQ KQLKTAVEMC AELDLKLRQT QVKESMRETD
     TQERLEKLIK EKDELIDLSV QRGKIIRDKQ VEIQELERKR QEAENGRRHA EDRFEKEAAA
     VNSELRVKEL REALERAEFS CNELKKEFEA FKKHSCELLE KEKELNCKLR HMII