CCD8A_ORYSJ
ID CCD8A_ORYSJ Reviewed; 552 AA.
AC Q93VD5; A0A0P0V470;
DT 03-APR-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Carotenoid cleavage dioxygenase 8 homolog A, chloroplastic;
DE Short=OsCCD8a;
DE EC=1.13.11.-;
DE AltName: Full=Protein D10-like;
DE Flags: Precursor;
GN Name=CCD8A; Synonyms=D10L; OrderedLocusNames=Os01g0566500, LOC_Os01g38580;
GN ORFNames=OsJ_02260, P0002B05.5, P0697C12.32;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=17655651; DOI=10.1111/j.1365-313x.2007.03210.x;
RA Arite T., Iwata H., Ohshima K., Maekawa M., Nakajima M., Kojima M.,
RA Sakakibara H., Kyozuka J.;
RT "DWARF10, an RMS1/MAX4/DAD1 ortholog, controls lateral bud outgrowth in
RT rice.";
RL Plant J. 51:1019-1029(2007).
CC -!- FUNCTION: May be involved in strigolactones biosynthesis.
CC {ECO:0000250}.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Highly expressed in panicles, inflorescences and
CC parenchyma cells of the root stele, and at lower levels in shoot apex,
CC leaf buds and xylem parenchyma cells of the stem.
CC {ECO:0000269|PubMed:17655651}.
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP003141; BAB63485.1; -; Genomic_DNA.
DR EMBL; AP003296; BAB64685.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF05277.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS72756.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ12371.1; -; Genomic_DNA.
DR EMBL; AK058473; BAG86705.1; -; mRNA.
DR RefSeq; XP_015627460.1; XM_015771974.1.
DR RefSeq; XP_015627470.1; XM_015771984.1.
DR RefSeq; XP_015627479.1; XM_015771993.1.
DR RefSeq; XP_015627487.1; XM_015772001.1.
DR AlphaFoldDB; Q93VD5; -.
DR SMR; Q93VD5; -.
DR STRING; 4530.OS01T0566500-01; -.
DR PaxDb; Q93VD5; -.
DR PRIDE; Q93VD5; -.
DR EnsemblPlants; Os01t0566500-01; Os01t0566500-01; Os01g0566500.
DR GeneID; 4327933; -.
DR Gramene; Os01t0566500-01; Os01t0566500-01; Os01g0566500.
DR KEGG; osa:4327933; -.
DR eggNOG; KOG1285; Eukaryota.
DR HOGENOM; CLU_016472_1_2_1; -.
DR InParanoid; Q93VD5; -.
DR OMA; RDFFAVK; -.
DR OrthoDB; 895046at2759; -.
DR PlantReactome; R-OSA-5367729; Strigolactone biosynthesis.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q93VD5; OS.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0010436; F:carotenoid dioxygenase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016121; P:carotene catabolic process; IBA:GO_Central.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; PTHR10543; 1.
DR Pfam; PF03055; RPE65; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Plastid;
KW Reference proteome; Transit peptide.
FT TRANSIT 1..43
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 44..552
FT /note="Carotenoid cleavage dioxygenase 8 homolog A,
FT chloroplastic"
FT /id="PRO_0000422059"
FT REGION 32..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 239
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 289
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 356
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 543
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 552 AA; 59916 MW; CA72C29D7E8CCB52 CRC64;
MATSLTLIAT PCTAPRSSSS FALAPRLPPR CSNATAARRR AVRATTLQSD QEPAGSGDSG
ATTTKLSAST SVRQERWEGD LPIEGCLPPW LNGTYIRNGP GMWDVGEHAF HHLFDGYATL
VRVSFRGGGG ARATGAHRQI ESEAYRAAVA RGRPVLREFS HCPAPAKSLL HRFGDLVGLV
TGAALTDNPN SAVLPLGDGR VMCLTETTKS SVLIDPDTLE TVGRFRYTDR LGGMVQSAHP
IVTDTEFLTL LPDLVRPGHL VVRMEAGSNE RKVIGRMDCR GGPSPGWLHS FAVTEKYAVV
PEMPLRYSSA SLLASELAPF YAFDWVPASG SYMHVMCKST GKTVASVEVP PFMAIHFINA
YEEEGDEAAV VVDCCEHYGD PAIIETLVLS RLRLLRGKDV LPNARVGRFR IPLDGSPFGE
LETALDPEEH GRGMDMCSIN PARLGRKYQY AYACGARRPC NFPNTLTKID LVEKKAKSWH
EEGSVPSEPF FVARPGATDE DDGVVISIVS SDDGEGYALV LDATTFEEIA RVRFPYGLPY
GFHGCWIPAT EE
