CCD93_XENTR
ID CCD93_XENTR Reviewed; 610 AA.
AC Q640U7;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Coiled-coil domain-containing protein 93;
GN Name=ccdc93;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in copper-dependent atp7a trafficking between
CC the trans-Golgi network and vesicles in the cell periphery.
CC {ECO:0000250|UniProtKB:Q567U6}.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000250|UniProtKB:Q567U6}.
CC -!- SIMILARITY: Belongs to the CCDC93 family. {ECO:0000305}.
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DR EMBL; BC082492; AAH82492.1; -; mRNA.
DR RefSeq; NP_001008173.1; NM_001008172.1.
DR AlphaFoldDB; Q640U7; -.
DR SMR; Q640U7; -.
DR STRING; 8364.ENSXETP00000011654; -.
DR PaxDb; Q640U7; -.
DR PRIDE; Q640U7; -.
DR GeneID; 493535; -.
DR KEGG; xtr:493535; -.
DR CTD; 54520; -.
DR Xenbase; XB-GENE-5914327; ccdc93.
DR eggNOG; KOG2701; Eukaryota.
DR InParanoid; Q640U7; -.
DR OrthoDB; 1091136at2759; -.
DR Proteomes; UP000008143; Chromosome 9.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR039116; CCDC93.
DR InterPro; IPR019159; CCDC93_CC.
DR PANTHER; PTHR16441; PTHR16441; 1.
DR Pfam; PF09762; CCDC93_CC; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Endosome; Protein transport; Reference proteome; Transport.
FT CHAIN 1..610
FT /note="Coiled-coil domain-containing protein 93"
FT /id="PRO_0000234609"
FT COILED 229..467
FT /evidence="ECO:0000255"
FT COILED 511..580
FT /evidence="ECO:0000255"
SQ SEQUENCE 610 AA; 70951 MW; 9B4F7F68AD597AE3 CRC64;
MAARGETPEV ETREDEEQGV KLAEILELLV AAGYFRARIK GLSPFDKVVG GMTWCITTCN
FDIDVDLLFQ ENSTIGQKIA LTEKIVSVLP KMKCPHRLEP HQIQGLDFIH IFPVIQWLVK
RAIETRQEMG DYIRSYSVSQ FHKEHSLPED QDFELRREKT VRTLSETLDV YRPRRKYKRQ
GGSSELMDEE SRVHSTLLEY GRRYGLSKQM KPEKPEDRRV PVPQGLVGKG EVREEEEELR
AEEELRIKAL MTEMAATGME EGRLTASTVG QIVGLQSKEI KQMVSEYAEK QSELSAEDRA
EYLGAAQQHR RKVASLSKLI GQRKKLLDQL QEKASELQSG CGETRKQLTE VTSHMEKLDQ
ELSVLENMES KADPSVLQKL RDLVAQNESL KAQEQQFRSK CREEMSRLQQ NIDGLKAAAT
EHGEEKEQTQ AFEQQYKAER EKLQKIRLLL ARRNREIAIL QRKIDEVPSR AELTQYQKRF
IELYGQVSAT HKETKQFFTL YNTLDDKKVY LEKEVNLLNS IHDNFQQAMA SPSARDQFLR
QMEQIVDGIR QSRNKMEKKK QENKMKRDQL NDEYLELLEK QRLYFKTVKE FKEECRKNET
LLSKMKGPTP