CCD97_MOUSE
ID CCD97_MOUSE Reviewed; 340 AA.
AC Q9DBT3; Q922V3;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Coiled-coil domain-containing protein 97;
GN Name=Ccdc97; Synonyms=D7Ertd462e;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and NOD; TISSUE=Corpora quadrigemina, Lung, and Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N, and NMRI; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-215, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Embryonic brain;
RX PubMed=15345747; DOI=10.1074/mcp.m400085-mcp200;
RA Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.;
RT "Phosphoproteomic analysis of the developing mouse brain.";
RL Mol. Cell. Proteomics 3:1093-1101(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney, Lung, Spleen, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK004762; BAB23543.1; -; mRNA.
DR EMBL; AK045509; BAC32401.1; -; mRNA.
DR EMBL; AK088221; BAC40219.1; -; mRNA.
DR EMBL; AK155466; BAE33278.1; -; mRNA.
DR EMBL; BC006752; AAH06752.1; -; mRNA.
DR EMBL; BC078634; AAH78634.1; -; mRNA.
DR CCDS; CCDS20994.1; -.
DR RefSeq; NP_083047.1; NM_028771.2.
DR AlphaFoldDB; Q9DBT3; -.
DR SMR; Q9DBT3; -.
DR STRING; 10090.ENSMUSP00000002683; -.
DR iPTMnet; Q9DBT3; -.
DR PhosphoSitePlus; Q9DBT3; -.
DR EPD; Q9DBT3; -.
DR jPOST; Q9DBT3; -.
DR MaxQB; Q9DBT3; -.
DR PaxDb; Q9DBT3; -.
DR PeptideAtlas; Q9DBT3; -.
DR PRIDE; Q9DBT3; -.
DR ProteomicsDB; 265366; -.
DR Antibodypedia; 48733; 133 antibodies from 20 providers.
DR Ensembl; ENSMUST00000002683; ENSMUSP00000002683; ENSMUSG00000002608.
DR GeneID; 52132; -.
DR KEGG; mmu:52132; -.
DR UCSC; uc009ftr.1; mouse.
DR CTD; 90324; -.
DR MGI; MGI:1196455; Ccdc97.
DR VEuPathDB; HostDB:ENSMUSG00000002608; -.
DR eggNOG; KOG3044; Eukaryota.
DR GeneTree; ENSGT00390000015495; -.
DR HOGENOM; CLU_058245_1_1_1; -.
DR InParanoid; Q9DBT3; -.
DR OMA; DSYDVRN; -.
DR OrthoDB; 1227195at2759; -.
DR PhylomeDB; Q9DBT3; -.
DR TreeFam; TF316152; -.
DR BioGRID-ORCS; 52132; 3 hits in 73 CRISPR screens.
DR ChiTaRS; Ccdc97; mouse.
DR PRO; PR:Q9DBT3; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q9DBT3; protein.
DR Bgee; ENSMUSG00000002608; Expressed in retinal neural layer and 243 other tissues.
DR ExpressionAtlas; Q9DBT3; baseline and differential.
DR Genevisible; Q9DBT3; MM.
DR InterPro; IPR040233; CCD97-like_C.
DR InterPro; IPR018613; Ccdc97-like.
DR PANTHER; PTHR31840; PTHR31840; 1.
DR Pfam; PF09747; DUF2052; 1.
PE 1: Evidence at protein level;
KW Acetylation; Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..340
FT /note="Coiled-coil domain-containing protein 97"
FT /id="PRO_0000286097"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 229..258
FT /evidence="ECO:0000255"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..260
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q96F63"
FT MOD_RES 47
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q96F63"
FT MOD_RES 215
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:15345747"
FT MOD_RES 272
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96F63"
FT MOD_RES 334
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96F63"
SQ SEQUENCE 340 AA; 38724 MW; DEFA1F2C03205BB2 CRC64;
MEAVAAAEVT ERKPDNDGVE PRVVHWGELS QTPIPSGPQE KETAERTPDI PNSGSSQAES
PAVSAMLHAI AASHLPVCSQ QQGEPDLTEP EKVAILGQLY HKKPLVFLER FRTGLREEHL
ACFGHLRGDH RADFYCAEVA RQGTARPRTL RTRLRNRRYA ALRELIQGGE YFSDEQMRFR
APLLYEQYIG QYLTQEELNA RTAAPQAPRS GSPGTPAYPL SDLLFQSYQE RELQQKLLQQ
QEEEEACFEE EEDSDEEDQR SDKDSEAWVP DSEERLILRE EFTSRMHQRF LDGKDGGFDY
STVDDNPDFD NLDIVARDEE DRYFDEEEPE DVSSAELGGD
