CCD9B_MOUSE
ID CCD9B_MOUSE Reviewed; 545 AA.
AC A3KGF9; Q3UV54; Q6DI90;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Coiled-coil domain-containing protein 9B {ECO:0000250|UniProtKB:Q6ZUT6};
GN Name=Ccdc9b {ECO:0000250|UniProtKB:Q6ZUT6};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP PROTEIN SEQUENCE OF 72-76, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=OF1; TISSUE=Hippocampus;
RA Lubec G., Sunyer B., Chen W.-Q.;
RL Submitted (JAN-2009) to UniProtKB.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 81-545.
RC STRAIN=C57BL/6J; TISSUE=Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Lung;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, and Embryo;
RX PubMed=24129315; DOI=10.1074/mcp.o113.027870;
RA Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA Bedford M.T., Comb M.J.;
RT "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT methylation.";
RL Mol. Cell. Proteomics 13:372-387(2014).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH75684.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK137584; BAE23419.1; -; mRNA.
DR EMBL; AL772255; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC075684; AAH75684.1; ALT_INIT; mRNA.
DR RefSeq; NP_001001982.2; NM_001001982.2.
DR AlphaFoldDB; A3KGF9; -.
DR BioGRID; 229507; 1.
DR STRING; 10090.ENSMUSP00000051853; -.
DR iPTMnet; A3KGF9; -.
DR PhosphoSitePlus; A3KGF9; -.
DR MaxQB; A3KGF9; -.
DR PaxDb; A3KGF9; -.
DR PeptideAtlas; A3KGF9; -.
DR PRIDE; A3KGF9; -.
DR ProteomicsDB; 265367; -.
DR Antibodypedia; 52258; 51 antibodies from 10 providers.
DR DNASU; 214239; -.
DR GeneID; 214239; -.
DR KEGG; mmu:214239; -.
DR UCSC; uc008lsn.1; mouse.
DR CTD; 388115; -.
DR MGI; MGI:2685199; Ccdc9b.
DR VEuPathDB; HostDB:ENSMUSG00000045838; -.
DR eggNOG; ENOG502S0JY; Eukaryota.
DR HOGENOM; CLU_026009_0_0_1; -.
DR InParanoid; A3KGF9; -.
DR OMA; RNWTRGT; -.
DR OrthoDB; 602532at2759; -.
DR PhylomeDB; A3KGF9; -.
DR TreeFam; TF336272; -.
DR BioGRID-ORCS; 214239; 1 hit in 72 CRISPR screens.
DR PRO; PR:A3KGF9; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; A3KGF9; protein.
DR Bgee; ENSMUSG00000045838; Expressed in hindlimb stylopod muscle and 48 other tissues.
DR InterPro; IPR029336; DUF4594.
DR PANTHER; PTHR15635; PTHR15635; 1.
DR Pfam; PF15266; DUF4594; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Direct protein sequencing; Phosphoprotein; Reference proteome.
FT CHAIN 1..545
FT /note="Coiled-coil domain-containing protein 9B"
FT /id="PRO_0000295734"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 52..99
FT /evidence="ECO:0000255"
FT COMPBIAS 203..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 404
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6ZUT6"
FT CONFLICT 151
FT /note="A -> T (in Ref. 1; BAE23419)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 545 AA; 58688 MW; 3E53AF89136D4041 CRC64;
MISCAEQRSR SRQGEADRAG SGGSSFPPAL APGSCFEILS APGISMHLAG PHKAESTMRR
HEEKDAELDR RIVALRKKNQ ALLRRYQEIE EDRRQAEQGG MAVTTPGLLQ PDSLTVTISQ
VPGEKRVVSR NWARAPLSPG VTTTLTDDED AADAPGTFSM GHRVELAVTM ENKAKAKRIV
SEKPTTQARS PRAKGTSGGG RSWRAPLQMT SSSDSAGKGV LEPRSPGVVS SPPPQQSLGL
SPEASWDYTQ WKQEREQIDL ARLARHRNPQ GDWSRPWDLD KAKSMPQNCH KPRDRDLAMG
SRKGPRTHQK PQHPPSSLDG KCRGGQSGRP SMTSTIGSNA QGKERLTGRA RRYDMKEDEM
LQSQEGSQSS TKTPSAEEEF VQKRNEREPD RQETVPATSP IPASPEGLKG ESGTSTASLA
PDSPQHSDLA PLDLSVGGAS SRKPGKSTCI LGPKAGAQQS PVSWPNGSEQ QTLGCTDHQP
GLEVHSCTES QRKAQTPEPM EDRAGKAGAQ ENLTPRSRPP RGIGPRARGT SKRSRAGGPG
PAGRC
