ID   CCLOP_ORYSJ             Reviewed;         506 AA.
AC   A9XMT5; Q5VRL9;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Protein CYCLOPS {ECO:0000303|PubMed:19074278};
DE            Short=OsCYCLOPS {ECO:0000303|PubMed:19074278};
DE   AltName: Full=Protein IPD3 homolog {ECO:0000303|PubMed:18761634};
DE            Short=OsIPD3 {ECO:0000303|PubMed:18761634};
GN   Name=IPD3 {ECO:0000303|PubMed:18761634};
GN   OrderedLocusNames=Os06g0115600 {ECO:0000312|EMBL:BAS95841.1},
GN   LOC_Os06g02520 {ECO:0000305};
GN   ORFNames=OSJNBa0019F11.17 {ECO:0000312|EMBL:BAD67908.1},
GN   P0541H01.39 {ECO:0000312|EMBL:BAD67768.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=19074278; DOI=10.1073/pnas.0806858105;
RA   Yano K., Yoshida S., Mueller J., Singh S., Banba M., Vickers K.,
RA   Markmann K., White C., Schuller B., Sato S., Asamizu E., Tabata S.,
RA   Murooka Y., Perry J., Wang T.L., Kawaguchi M., Imaizumi-Anraku H.,
RA   Hayashi M., Parniske M.;
RT   "CYCLOPS, a mediator of symbiotic intracellular accommodation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:20540-20545(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   FUNCTION, TISSUE SPECIFICITY, INDUCTION BY ARBUSCULAR MYCORRHIZA FUNGUS,
RP   AND DISRUPTION PHENOTYPE.
RX   PubMed=18761634; DOI=10.1111/j.1469-8137.2008.02612.x;
RA   Chen C., Ane J.M., Zhu H.;
RT   "OsIPD3, an ortholog of the Medicago truncatula DMI3 interacting protein
RT   IPD3, is required for mycorrhizal symbiosis in rice.";
RL   New Phytol. 180:311-315(2008).
CC   -!- FUNCTION: Involved in arbuscular mycorrhizal (AM) symbiosis. Required
CC       for fungal infection in roots and arbuscule development during AM
CC       symbiosis. {ECO:0000269|PubMed:18761634, ECO:0000269|PubMed:19074278}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:A9XMT3}.
CC   -!- TISSUE SPECIFICITY: Highly epressed in roots. Expressed at very low
CC       levels in leaves, stems and panicles. {ECO:0000269|PubMed:18761634}.
CC   -!- INDUCTION: Induced in roots 7 weeks after inoculation with the
CC       arbuscular mycorrhiza (AM) fungus Glomus intraradices.
CC       {ECO:0000269|PubMed:18761634}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC       conditions, but roots of mutant plants are impaired in the interaction
CC       with the arbuscular mycorrhiza (AM) fungus Glomus intraradices.
CC       {ECO:0000269|PubMed:18761634, ECO:0000269|PubMed:19074278}.
CC   -!- SIMILARITY: Belongs to the CYCLOPS family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD67768.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAD67908.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAF18528.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; EF569223; ABU63670.1; -; mRNA.
DR   EMBL; AP001389; BAD67768.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP002837; BAD67908.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008212; BAF18528.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014962; BAS95841.1; -; Genomic_DNA.
DR   AlphaFoldDB; A9XMT5; -.
DR   SMR; A9XMT5; -.
DR   STRING; 4530.OS06T0115600-01; -.
DR   PaxDb; A9XMT5; -.
DR   PRIDE; A9XMT5; -.
DR   EnsemblPlants; Os06t0115600-01; Os06t0115600-01; Os06g0115600.
DR   Gramene; Os06t0115600-01; Os06t0115600-01; Os06g0115600.
DR   eggNOG; ENOG502QQ45; Eukaryota.
DR   HOGENOM; CLU_515253_0_0_1; -.
DR   OMA; FLAKAWF; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0036377; P:arbuscular mycorrhizal association; IMP:UniProtKB.
DR   InterPro; IPR040036; CYCLOPS.
DR   PANTHER; PTHR36890; PTHR36890; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..506
FT                   /note="Protein CYCLOPS"
FT                   /id="PRO_0000444701"
FT   REGION          193..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..434
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          441..506
FT                   /evidence="ECO:0000255"
FT   MOTIF           415..418
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        409..430
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   506 AA;  56092 MW;  08FC2ED8E55CDF80 CRC64;
     MEGRGLSELF RNTSEDMFLK AMMENSMGVA AAAPSMEMMG FRNLSQGFRE DSEELFNSWL
     MNGEIPGFSA MNNRPRQPSR LSSEAAGFPN QQHEIAQEHF PTDNLIPQNL AVHSEFTMNH
     NQQQLKNAAE KGMQASDLLL AKAWFHSTQP MTRSRSSELR KRYAAMQSNM PPITTETIET
     ANKLRQDLTN ASTVNSAPMS NTPSQTPTFV SPSSSSTSPL DNPHIVAQDT ITSVVSMLKD
     TLERKKLSSH ANGDTSSGIS FGFYDSQHFQ QNILGGTDIF PLVTTSQIQD SVMLPKVERP
     TEQGSGNFVA PANQVWLGTA SREPSQSGSS TAIPAPSAGF EVCDDLPPIG QAMTVCESTR
     TNAANGNGTA DCRSKGKDFR ERILKENLKD DRKKGSLTRM GSISSEQADK GDPTKKRRVE
     RSRKMAEAKE RSSTPVIPSD IQVVLKRCET LEKEVRSLKL NLSFMNRKDS EQTKQIEELQ
     KQNEDLVEEK ERLLEEIERI VSDTNT