ID   CCM1_CANAL              Reviewed;         768 AA.
AC   Q5A8W9; A0A1D8PQ70; Q5A8P4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; OrderedLocusNames=CAALFM_C603440WA;
GN   ORFNames=CaO19.13127, CaO19.5704;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; CP017628; AOW30274.1; -; Genomic_DNA.
DR   RefSeq; XP_718046.1; XM_712953.1.
DR   AlphaFoldDB; Q5A8W9; -.
DR   STRING; 237561.Q5A8W9; -.
DR   GeneID; 3640274; -.
DR   KEGG; cal:CAALFM_C603440WA; -.
DR   CGD; CAL0000174731; orf19.13127.
DR   VEuPathDB; FungiDB:C6_03440W_A; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_019745_0_0_1; -.
DR   InParanoid; Q5A8W9; -.
DR   OrthoDB; 531312at2759; -.
DR   PRO; PR:Q5A8W9; -.
DR   Proteomes; UP000000559; Chromosome 6.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 2.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 6.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..90
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           91..768
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402256"
FT   REPEAT          274..308
FT                   /note="PPR 1"
FT   REPEAT          309..344
FT                   /note="PPR 2"
FT   REPEAT          347..381
FT                   /note="PPR 3"
FT   REPEAT          382..417
FT                   /note="PPR 4"
FT   REPEAT          418..452
FT                   /note="PPR 5"
FT   REPEAT          634..664
FT                   /note="PPR 6"
FT   REGION          28..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          90..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          583..609
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   768 AA;  88529 MW;  7C4C5CE8D08FA0BE CRC64;
     MIRLIRWNNV QSLVFKRCLF VPSNSLTNKR KRRIPPSKPR SSNRKDGDIE PYRMTDQNQT
     PNTGSIARLP AEVKKELKDL RSFTKVIAQH LKPEQENDSL TSAEKPDTSQ LPPIDIEEAT
     DDIFGEISGT KKLSANAVPP PPPPPGLDIP DEIKERLGLL SELLVPAKTS NNKLPEKQVE
     NNWKLLLSQL DQAGGLSGLS KRSVSKFFSK IPPKNLKNLI PMIENMYNKA EMSIPHPIYY
     MFVRSLTLGD KISDSQMQLI NKYFQEISKQ TDLKIDHYET MILAYVKNNH MEKIDGILAQ
     MKKKNIEISK MIYTSIVRGY IFYQKDHQRA LDTFDSMKFL SQKTQPDEKV YTDVIVSCVM
     HREIERALDL YYELKDKGMN VNQNLLSTLA KGCSRSKQFK TQAWNFLFQV YDHGWVPNLQ
     TYEHMLYIAA RDGDVELTRV LFYKMLQTNS VTIRAFRYLI LSYSKYVPPH KRKEKHLILL
     NHKGQLFRQN ILQDVDFSKP VHGFPFLPSS HIPDSKFVLA ESSAIWAHTV MNNPSFLRQQ
     TLVASYVSIA LELGDFTEFK DRFDSASYLN TDGIPKVREI EIIEPRQDEP TEKATTTEEQ
     NASSETDNNS LIRSPILNQL QQNINDNQFK APRDSYLYNL AIKAAGKFKN YGFAQEILHE
     RGQFRKSNSF KLLSPKQQNQ DDFQFAGYLV ECWTNMNLLE DAYAVVLSSV DRFPWSWREL
     GVLNNAAMKL GSLELAEAVR KVAQVTQVKH HGKIKRQDFK TYVMKRGY