ID   CCM1_CANDC              Reviewed;         765 AA.
AC   B9WJ16;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; ORFNames=CD36_63520;
OS   Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS   NRRL Y-17841) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=573826;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX   PubMed=19745113; DOI=10.1101/gr.097501.109;
RA   Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA   Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA   de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA   Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA   Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT   "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT   Candida albicans.";
RL   Genome Res. 19:2231-2244(2009).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; FM992693; CAX41235.1; -; Genomic_DNA.
DR   RefSeq; XP_002421078.1; XM_002421033.1.
DR   AlphaFoldDB; B9WJ16; -.
DR   SMR; B9WJ16; -.
DR   STRING; 42374.XP_002421078.1; -.
DR   EnsemblFungi; CAX41235; CAX41235; CD36_63520.
DR   GeneID; 8048700; -.
DR   KEGG; cdu:CD36_63520; -.
DR   CGD; CAL0000171461; Cd36_63520.
DR   VEuPathDB; FungiDB:CD36_63520; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_019745_0_0_1; -.
DR   OrthoDB; 531312at2759; -.
DR   Proteomes; UP000002605; Chromosome 6.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 6.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Repeat; Transit peptide.
FT   TRANSIT         1..63
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           64..765
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402258"
FT   REPEAT          274..308
FT                   /note="PPR 1"
FT   REPEAT          309..344
FT                   /note="PPR 2"
FT   REPEAT          347..381
FT                   /note="PPR 3"
FT   REPEAT          382..417
FT                   /note="PPR 4"
FT   REPEAT          418..452
FT                   /note="PPR 5"
FT   REPEAT          631..661
FT                   /note="PPR 6"
FT   REGION          26..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          92..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          585..609
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        588..609
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   765 AA;  87981 MW;  CED012F460A94872 CRC64;
     MIRLIRGNNV PSLVFKRSLF VPSNSLTNKR KRRIPPLKPR SSNKEGGDIK QSRITDRNQT
     SRTVGVSEKL PTQIKKELKD LRSFTKVIAQ HLKPEQENDS LTSAEKPDTS QLPPIDIEEA
     TDDIFGQISG TKKSSVEVAP PPPPPGLDIP DEIKERLGLL SELLVPEKSS NSKLPEKQVE
     NNWKLLLSQL DQAGGLSGLS KRTISKFFSK IPPKNLKGLI PIIENMYNKA EMSIPHPIYY
     MFVRSLTLGD KISDTQMQLI DKYFQEISKQ TDLKIDHYET MILAQVKNNH MEKIDGILAL
     MKTKNIEISK MIYTSIVRGY IFYQKDHQKA LETFDSMKFL SQKTQPDEKV YTDVIVSCIM
     HREIEKALDL YYELKDKGMN VNQNLLSTLA KGCSRSKQFK TQAWNFLFQI YDHGWVPNLQ
     TYEHMLYIAA RDGDVELTRA LFYKMLQTNS VTVRAFRYLI LSYSKYVPPH KRKERYLILL
     NHKGQLFREN ILQDVDFSKP IHGFPFLPSS HIPDSKFVLA ESSAIWAHTV MNNPSFLRQQ
     TLVASYVSIA LELDDFTEFK NRFNSASYLN KDGIPKVREI EIIEPQQDEP TETVTATEQQ
     NTSSNTSVIR SPILNQLQQN INDNQFKAPR DSYLYNLAIK AAGKFKNYGF AQEILHERGQ
     FRKSNSFKSL SPKQQHQDDF QFAGYLVECW TNMNLLEDAY AVVLSSIDRF PWSWRELGVL
     NNAAMKLGSL ELAEAVRKVA QVTQVKHHGK IKRQDFKTYV MKRGY