ID   CCM1_CANGA              Reviewed;         830 AA.
AC   Q6FVC6;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; OrderedLocusNames=CAGL0E02959g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380951; CAG58737.1; -; Genomic_DNA.
DR   RefSeq; XP_445818.1; XM_445818.1.
DR   AlphaFoldDB; Q6FVC6; -.
DR   STRING; 5478.XP_445818.1; -.
DR   PRIDE; Q6FVC6; -.
DR   EnsemblFungi; CAG58737; CAG58737; CAGL0E02959g.
DR   GeneID; 2887338; -.
DR   KEGG; cgr:CAGL0E02959g; -.
DR   CGD; CAL0128648; CAGL0E02959g.
DR   VEuPathDB; FungiDB:CAGL0E02959g; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_334653_0_0_1; -.
DR   InParanoid; Q6FVC6; -.
DR   OMA; RALYYKY; -.
DR   Proteomes; UP000002428; Chromosome E.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0019843; F:rRNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:EnsemblFungi.
DR   GO; GO:0000963; P:mitochondrial RNA processing; IEA:EnsemblFungi.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:2000234; P:positive regulation of rRNA processing; IEA:EnsemblFungi.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0016072; P:rRNA metabolic process; IEA:EnsemblFungi.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 1.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 2.
DR   PROSITE; PS51375; PPR; 3.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..21
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..830
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402259"
FT   REPEAT          312..342
FT                   /note="PPR 1"
FT   REPEAT          349..383
FT                   /note="PPR 2"
FT   REPEAT          698..732
FT                   /note="PPR 3"
SQ   SEQUENCE   830 AA;  95610 MW;  5BF1200CA071660C CRC64;
     MRTVLPVHRF VRTVYLPARR LVKANVGAQK IAPAASSAIL PKDLDIDIRG IEDPKVLEMK
     VKQLQEFTRN IKTEIKRRAK QKHTEEQPLE LSNNEDISAV FNAVVNTPKK ADSIGKGITE
     KLMENTVDQI IDNVVPKAIQ ERIADKSLMV RALVRTSVHT PIESNMLVKK LAESEMRLKG
     LPQEDIRTFL KKSIKNLNFT NILELDKMLL EYVGNDISKF SDNMYKCLFS NLSKLNAQST
     QHSKDDLVIK MFNKLLKRYD TNLNTTNANV WNEKMTNVIL SYCINYSIKL KDFEITDKFV
     SKFKNDYKLL PDKQNYTSII HFYSKLGLSD KAWDTFDTMK FLSRSHAPDT KAYNSVLMLC
     KQEKDFRKTI DLYHEMVDKK VPMDARTYTT MIHTLAAAST DSYTSEGKSD SLRILGWKLI
     NELSKNLQYD VMKNKHILIS MLSLSAYDGD LGMARALYYK IFHQKSDELY ATMNPAQLEN
     LSAKDILSYV LDPKVLNYLL LAYSRYDKGR LPLILANDEG STLRRNVINA VDFGGHSSEM
     SALELANKIT IPFLPYSEIS ENWQIIAESR ALWLFNLEYG GITDISLTSS IQENAMIYRD
     QAIDINEFKL KIMNDLIEWK TENLNNTVLN PTLLQTFLTI PLKSGNREEF YSRLNAFTFQ
     QHNLNSVMEK FYEYKPESEE YNDCLKYFES LKRKILMSNS HYDLVMKAAT KFGDIDAANQ
     VWKDRGEYRK TTSFAKLPTK DRIISDSNFA KLMVEFFVSQ RLYSDAMAVV LSSKNFIKWD
     YSMVKSLHHG LIEAEDIINI EKLLDVVNRS KGTKKAVDVI NEQIEELKLS