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CCM1_KOMPG
ID   CCM1_KOMPG              Reviewed;         725 AA.
AC   C4R5P7;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; OrderedLocusNames=PAS_chr3_1225;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; FN392321; CAY70883.1; -; Genomic_DNA.
DR   RefSeq; XP_002493062.1; XM_002493017.1.
DR   AlphaFoldDB; C4R5P7; -.
DR   STRING; 644223.C4R5P7; -.
DR   PRIDE; C4R5P7; -.
DR   EnsemblFungi; CAY70883; CAY70883; PAS_chr3_1225.
DR   GeneID; 8200322; -.
DR   KEGG; ppa:PAS_chr3_1225; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_019745_0_0_1; -.
DR   InParanoid; C4R5P7; -.
DR   OMA; RALYYKY; -.
DR   Proteomes; UP000000314; Chromosome 3.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..725
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402266"
FT   REPEAT          189..223
FT                   /note="PPR 1"
FT   REPEAT          224..259
FT                   /note="PPR 2"
FT   REPEAT          260..290
FT                   /note="PPR 3"
FT   REPEAT          296..330
FT                   /note="PPR 4"
FT   REPEAT          333..363
FT                   /note="PPR 5"
FT   REPEAT          401..435
FT                   /note="PPR 6"
FT   REPEAT          601..635
FT                   /note="PPR 7"
SQ   SEQUENCE   725 AA;  84412 MW;  4E7501F424D83710 CRC64;
     MRLSRIGTPK VSVTRVIPVR NVVIARRKPV RASNTDAKTW LMKEEQRRIR QKEQEMKQRL
     EELERFKTKV QKSYIRKEDR HLAQEIEKDL DIITDDYNLD SDVDLVFGEL MQAEEQPKSL
     KSLPGASDAS DNTDKSVELF SFPSPNLTLP EKVIHHIGPL VKHISNPENI QWGRLLLDLE
     KNQGFNGLSA VDVTRLIQNI PKEEKYQHMS LIHEMMFNSG ISPDRYLTDL MMTAFSERSY
     YEPLVEALFQ DYDINGWAPT DYTFGALIKV YSKGKKLDKI NNLLNQMKLK YHKEPNKKIY
     TMVLQTCMKI DDYKKTSEVF DAMKFNSVAT NPDTTAYGSM ILMHVLNDNV EAALDLYDNL
     ETEPDETILL ALARGCSSRK VLINRGWDFI IEYYKRKFPL NEKLMTVMMY LTSRDGDLSL
     TRAIYNTIHE SRFKMTESFS MNKNDGIALN VLLRGYFKYP DNHTVQSKTN DAVVALRRST
     LALNHFGYHP KATPFLPVNE LEEKHILPEV QAIWSYIILH YPDIVTSELV GTYLMILATR
     GSMADFNKAF EELTLKPVFE QVDNAVAVEE ESEQSSELSD LRLTPLAIRL SSNIQIKYPR
     NHDIYHIALQ ACINNKDIEL GQRIWQERGR FRKTPEFSMQ PRNVKHNQDF EFARDMLKLL
     VNCNELNDAC RLLLSTETQF NWEWTYVKPV YIMAEQLGDE YAKKVVRRVV RNKKSKWREE
     YLQGM
 
 
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