ID   CCM1_PICST              Reviewed;         775 AA.
AC   A3LRH4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; ORFNames=PICST_30689;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000497; ABN65737.2; -; Genomic_DNA.
DR   RefSeq; XP_001383766.2; XM_001383729.1.
DR   AlphaFoldDB; A3LRH4; -.
DR   SMR; A3LRH4; -.
DR   STRING; 4924.XP_001383766.2; -.
DR   EnsemblFungi; ABN65737; ABN65737; PICST_30689.
DR   GeneID; 4838273; -.
DR   KEGG; pic:PICST_30689; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_019745_0_0_1; -.
DR   InParanoid; A3LRH4; -.
DR   OMA; RALYYKY; -.
DR   OrthoDB; 531312at2759; -.
DR   Proteomes; UP000002258; Chromosome 3.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR033443; PPR_long.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF17177; PPR_long; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 5.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..18
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..775
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402267"
FT   REPEAT          289..323
FT                   /note="PPR 1"
FT   REPEAT          324..355
FT                   /note="PPR 2"
FT   REPEAT          362..396
FT                   /note="PPR 3"
FT   REPEAT          397..432
FT                   /note="PPR 4"
FT   REPEAT          433..467
FT                   /note="PPR 5"
FT   REGION          35..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  89001 MW;  6EEC67D9DE0C13B7 CRC64;
     MLRYARTVRF SQVGNSVRTS SGSFGPIRTI FISSHDRKSP SHSLSPISNL PNHNDSSTER
     ARKTLDDDFQ RKIKYDELKT RKRIEDLRAL TKKVSQLVKQ KQELSKIAKI PVPSDEIKKL
     KSVEDVVKVT KSQHVATVRT NIPEPETVTT HIEKEESEFV MEQNAFIVPA TPIPEEIAKR
     LGLALRYLVS ETNQNWTLVL DQLKADRGFK DLPYTTVVDF LTKIPASELQ KVIPKVDQLL
     KEAKIPKTAK ILNLYIASLA SGSAVPNQVI QILENYCKRI RKLKKGKLPK RTCEVMVQAY
     GKNGNINRIQ DLLSEMKLHK IEISGMALTN ILATCVYKAR DHKQAVEIFD TMRFQKEVYK
     PGTRAYQDII VSYVNNDDIE KAIDIYREMI TEKIEPNQQI MVALARGCAS REAFKFKSWD
     FIFEINRNNW TPTLPTYEYM LYLSSRDGDL ALTRALYSRL LKDNTVSLRS FNFLLLAYSK
     ARLSDDLGEP FLINADEKGR KFRFNVIDRS GISDPTNQFP FLPFNELTTK EQIMAESSAI
     WAHACLNNSE LINSESTTSY LNIASERGTL SDFIDRMEGS TFLDEKINNV LSGVVIEEPD
     VVVETTDFLT QKSSAHEKYD ETSIVKSPIL KSIQSKRTPR VSLTYVVALK AAGKFNNYNF
     ANRIWQERGK FRKTETFKKL PRTEKDKLDF QFATQMVRTL TELNLLEDAL AVLKSTEYQF
     RWTWKELDVL KSAAIRQGNT NVAQTVRSIA RRAQLTYEGK IRRKDYKRYV MQRGY