ID   CCM1_VANPO              Reviewed;         867 AA.
AC   A7TMW6;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; ORFNames=Kpol_1051p2;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; DS480426; EDO16354.1; -; Genomic_DNA.
DR   RefSeq; XP_001644212.1; XM_001644162.1.
DR   AlphaFoldDB; A7TMW6; -.
DR   STRING; 436907.A7TMW6; -.
DR   PRIDE; A7TMW6; -.
DR   EnsemblFungi; EDO16354; EDO16354; Kpol_1051p2.
DR   GeneID; 5544517; -.
DR   KEGG; vpo:Kpol_1051p2; -.
DR   eggNOG; ENOG502QUX2; Eukaryota.
DR   HOGENOM; CLU_334653_0_0_1; -.
DR   InParanoid; A7TMW6; -.
DR   OMA; RALYYKY; -.
DR   OrthoDB; 531312at2759; -.
DR   PhylomeDB; A7TMW6; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 2.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..96
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           97..867
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402269"
FT   REPEAT          337..371
FT                   /note="PPR 1"
FT   REPEAT          374..408
FT                   /note="PPR 2"
SQ   SEQUENCE   867 AA;  100099 MW;  EC56F88E513322F1 CRC64;
     MLRYTRNYRL HNVASSLILK RTAIIPSLQG LRRGNFSQDD TTNLNNKKRR KRKVTSISLD
     DLNSVNLKKV NTKELEFKVR QLKEFTKNLK AQIKRSESRN EKRETEDDID LEEINKDADS
     VFENLSNHER RKNHKVQNHL GIPIGNSQNQ STNLSSLILG SSLEQAQKFL PSTLVTRLND
     NNLVLKCLTD KTRQNWNPII KSISKNREGL NGIGKNKLNS TLLSSVKGLY FDNIERLDKM
     LLEYVDNDIT KFTTEMYLSL FENLSNIKLT DPNMSNEVIV KMKELLERYD EALIKGTDTK
     MTQYILNNGI KFASKLNNHE HMEYFLTKFK GYGIIPNRIN YTTVLQYYIR MGISKKSWDI
     FDTMKFLSKE HAPDLIAYNS VLTLCSRDKD YSKALDIYNE MVNSGINPGT STRTIMAKIL
     AIASRDSFTS EGKSESLRLL GWKFIHEIIE TTGSKLSHKS LESMIALAAY DGDVGMSRAL
     YHCYVTTKYR NVVQNWVGKR DYVKIWKSVL DPRMLNYLFL AYSNYNSNKL PLLLGYEQGI
     LLRRNIINSV DYSGRSEFDD DLGVLLPFLP VTEIKHNWEL LAESRAIWHF NLEYGGSTSL
     RSTSESIVDK STIMTAVENS KTIDDFKWNI FSKIHELKSQ TINTDVLNSI VLNTYLTIPI
     KLHDKKEFVL RLKEFTFQQH DFDSKIESFY LESNNKMVED NDKNSSSPST SEDTSIELAE
     DPNDLLAHYI LSLKHKILAN CSTYELTMKA ASKFNDIKLA TEAWEERGKF RKSSSFQKLA
     QNNRMESDTK FAELMVAFFS SQKMYTDALH VVMSSKRYID WKYPMVKNLH RGLLEIEDSR
     SIDILLDIVN RKSKVQTIEE TISSLTL