ID   CCM1_YARLI              Reviewed;         773 AA.
AC   Q6CHP9;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; OrderedLocusNames=YALI0A06611g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; CR382127; CAG83738.1; -; Genomic_DNA.
DR   RefSeq; XP_499812.1; XM_499812.1.
DR   AlphaFoldDB; Q6CHP9; -.
DR   SMR; Q6CHP9; -.
DR   STRING; 4952.CAG83738; -.
DR   EnsemblFungi; CAG83738; CAG83738; YALI0_A06611g.
DR   GeneID; 2905884; -.
DR   KEGG; yli:YALI0A06611g; -.
DR   VEuPathDB; FungiDB:YALI0_A06611g; -.
DR   HOGENOM; CLU_361776_0_0_1; -.
DR   InParanoid; Q6CHP9; -.
DR   OMA; CIADASE; -.
DR   Proteomes; UP000001300; Chromosome A.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR033443; PPR_long.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 1.
DR   Pfam; PF17177; PPR_long; 1.
DR   TIGRFAMs; TIGR00756; PPR; 2.
DR   PROSITE; PS51375; PPR; 5.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..23
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..773
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402270"
FT   REPEAT          220..254
FT                   /note="PPR 1"
FT   REPEAT          255..285
FT                   /note="PPR 2"
FT   REPEAT          294..328
FT                   /note="PPR 3"
FT   REPEAT          331..365
FT                   /note="PPR 4"
FT   REPEAT          366..400
FT                   /note="PPR 5"
FT   REGION          89..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..103
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  88107 MW;  817C47C5CADEC3FA CRC64;
     MLRARLLVPL VRPALVHRLD RCYSTALGSR FRKSNAVRSE LKFDFPDVPV KEELFVQETP
     DKPLKENKTH VSDEDIDSLF DSLMSDHKAA EATEQHKELP PAEQERPSGA NTHTAPIKHD
     TKSPMEYLAK SKLTPHVSRQ VAKAMAGSPT QLLLATPASH HISTPAYQND LWKHVISTLN
     TSKFQIPDFN SLMTTIPVDI RAQFLPQIEE WISQRGVKPS AITYGQVMLG YAEDGNVEKV
     EERFRQMIDN NITPTVHTYA HRLKACDKRG DLKQAMEIFD DLKLAQQLYG IRPNQVIFTT
     LISTSLRNHK VELASQIFEY MKYASLETQP TAHTYNSLIT ASAIRSNTER ALDLFEEMKQ
     KSVANVRTYQ SLILACLRQE KYHLKAWELL LELREQHSES FYSRHTLVVV FQAAAVTGDL
     VFLRSLYKQL CMSPETYPDA ILTQLLMQAY ARYDTRTKPV ASSALRATWG RLYGGNAQEM
     MRGFLFPDIE GMVQLNEEHP GMIPPFLPTN TIESLSFDRK KIIAESRAIF QFLKNNKPQL
     LDNIAATDYL KAGARHRDFP EFLRRYNEVS VGAGEAEGAV ISPSEMKTYS ARQKKPQRYD
     LQTQFSPAPR SDAHFFIALN AVQADCIADA SERDPNLNHP LRRLTPQEMT DRLEFSQDVW
     VERGKWRKSD AYKNKYRTEA QQISADYNFA LKIINALAAL KQLGEAAAIL SATPATFNWK
     KHDLAFFHNV AQAFYHEEAM KQIHKAVSRS KHLDEVIRNP DSEKSAEFDV FSI