ID   CCM1_YEAS1              Reviewed;         864 AA.
AC   B3LI79;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   AltName: Full=COB and COX1 mRNA maturation protein 1;
DE   AltName: Full=Required for respiratory growth protein 2;
DE   Flags: Precursor;
GN   Name=CCM1; Synonyms=DMR1, RRG2; ORFNames=SCRG_00869;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
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DR   EMBL; CH408044; EDV10100.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LI79; -.
DR   PRIDE; B3LI79; -.
DR   EnsemblFungi; EDV10100; EDV10100; SCRG_00869.
DR   HOGENOM; CLU_334653_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 2.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Repeat; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..864
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402271"
FT   REPEAT          319..353
FT                   /note="PPR 1"
FT   REPEAT          356..390
FT                   /note="PPR 2"
SQ   SEQUENCE   864 AA;  101417 MW;  98905CBFA2FB6A3F CRC64;
     MYMARCGPKN NVLCFPFQLS FLFSKRLINK RFKYTLQTED EKNMMGSLSK NKIITPEDVE
     FKLAQLREFS NTLKERIHNT KSVNSDGHQS NSIAPISEDS RNVNVTKISS VPNEEKSKNL
     SDLIHSSFLE KMDHLVPKVI RERVADDDIL AKNLFDRSHS NWAPVIDRLY VSEKRFMDID
     SREFSVWLNG TVKYLPFHSI LHLDEMLLEQ INGDVVKFNT HMYECIFNNL GNLKPTNFNQ
     DGTNDKVILK MKELLERYDK ALKITEERIN KKEGFPSKVP KMTQAILNNC LKYSTKCSSF
     HDMDYFITKF RDDYGITPNK QNLTTVIQFY SRKEMTKQAW NTFDTMKFLS TKHFPDICTY
     NTMLRICEKE RNFPKALDLF QEIQDHNIKP TTNTYIMMAR VLASSSSNAV VSEGKSDSLR
     LLGWKYLHEL EDKNLYRHKK DDLNLFLAMM ALAAFDGDIE LSRALYYLFI AKKYKTLCAN
     WKGNILVDQD TIWKSTLMPE MLNYLMLAYA RFDPRNLPVL SGYEKGIELR RKFLREFDSS
     MRLDDTDKLV KFKLPFLPIS DLNSEAQVLA ESNAIWSFNL ENGGTRNTLT SSNEAALEDI
     KKYRQLLDSF AQEAEDFNEF KFKVMYEVTK MQRESINVNV FNKISLHTYL SIPINLKQQK
     EFLRRLTFFT FQQHEFEAVI KRLYEGYRNI PSSHTRDQNS ISTEAISVSK PETTEDLNLI
     MHDIWYITCL RHKIMMDTTL YELVMKAAIE FQNEDLAKKV WNDRGKFRTT VPFLKMDQRI
     RIAKDQKFAH LMVEFFTKQG KYSDAIAIIL SSKNRFNWTY SMVRNLHKAL EEIEDRNSVE
     ILLDVVNKKS HAKALKWEEQ ELNM