ID   CCM1_ZYGRC              Reviewed;         839 AA.
AC   C5E042;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Mitochondrial group I intron splicing factor CCM1;
DE   Flags: Precursor;
GN   Name=CCM1; OrderedLocusNames=ZYRO0G09592g;
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC       I introns in mitochondrial encoded transcripts. Maintains the stability
CC       of the small subunit mitochondrial 15S rRNA and thus the expression of
CC       the mitochondrial genome (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCM1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928179; CAR29476.1; -; Genomic_DNA.
DR   RefSeq; XP_002498409.1; XM_002498364.1.
DR   AlphaFoldDB; C5E042; -.
DR   STRING; 559307.C5E042; -.
DR   EnsemblFungi; CAR29476; CAR29476; ZYRO0G09592g.
DR   GeneID; 8206215; -.
DR   KEGG; zro:ZYRO0G09592g; -.
DR   HOGENOM; CLU_334653_0_0_1; -.
DR   InParanoid; C5E042; -.
DR   Proteomes; UP000008536; Chromosome G.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF01535; PPR; 1.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 2.
PE   3: Inferred from homology;
KW   Mitochondrion; mRNA processing; mRNA splicing; Reference proteome; Repeat;
KW   Transit peptide.
FT   TRANSIT         1..59
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           60..839
FT                   /note="Mitochondrial group I intron splicing factor CCM1"
FT                   /id="PRO_0000402275"
FT   REPEAT          313..347
FT                   /note="PPR 1"
FT   REPEAT          350..384
FT                   /note="PPR 2"
SQ   SEQUENCE   839 AA;  98048 MW;  9A2D67AD23F4C4C0 CRC64;
     MLSLKSRGSW NVLRWIQVPR RTAVIPAKPS PMRRKRRRIK NVSSKDLDLR GIDPQDSRAL
     EFKVKQLQEF TRNLKEQFKL ADSNTKKLEA EEELAKSIPE DDDKRADELF GKLEAPAFEK
     PLPQPNLSTL ILSAENQQLK KLIPVEIKER INDDGFLLAR LIDKDNQNWN DIISKLYTTE
     KRLSDISMPI ISSGILRKVK NLSYENIEKL DIMLLETKNG DITCFNRLMY ETLLLNLSNL
     RPPTSGEEDK VTMKMRQLLE RYDKSKEISP DVPSKMTQFS LNCCLKYSTK SVSFENMEYF
     LSKFKNDYGI TPNRENYTTV IQFYVKFGVS KQAWDVFDTM KFLSSSHAPD VTTYNSVLHL
     CNRERDYAKA IDLYEEMLDR QLQPSIQTLN IMAKTMARAS ADNVISEGKA DSLRLLGWKY
     IHTLESTFDH TKHETHFYHT LEAMMALAAY DGDVGFARAL YYKYTTRKYK EVVKYWKGKF
     DSQKIWQTAL DPQLFNLLLL AYANFRPNKL PILLGYEKGI KLRRNILNSV DYAGRYDLDD
     EIKVQLPMLP ISDMNQAWQI LAESRALWQF NLEFGGYYDL RDTPEGFDTT RLQEMVSKSA
     TQDELQFNIL HQVSQWKFQL VNHSILNPKS LTTFLTIPIK NGDRIEFMLR LKEFTFQQND
     LESRIEKLYK GLKLVESRVE PNSHERDLAI NQIEMDENVK WFASMKHKIV AKNYIYELMM
     KAASAFKDSA ISKDAWQSRG EYRKTKLFQQ MDSKRRIESD TQFAALMVQF FARQNMLTDA
     LAIVMSTRKF IDWKYHMVKG LHEGLVKLED EKSISILLDI VNKKSSIELL DEKIRDFQL