ID   CCMB_BRADU              Reviewed;         222 AA.
AC   P30964;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Heme exporter protein B;
DE   AltName: Full=Cytochrome c-type biogenesis protein CycW;
GN   Name=cycW; Synonyms=ccmB; OrderedLocusNames=blr0468;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=USDA 110RIF15;
RX   PubMed=1850420; DOI=10.1016/s0021-9258(20)89520-9;
RA   Ramseier T.M., Winteler H.V., Hennecke H.;
RT   "Discovery and sequence analysis of bacterial genes involved in the
RT   biogenesis of c-type cytochromes.";
RL   J. Biol. Chem. 266:7793-7803(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CcmB/CycW/HelB family. {ECO:0000305}.
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DR   EMBL; M60874; AAA26193.1; -; Genomic_DNA.
DR   EMBL; BA000040; BAC45733.1; -; Genomic_DNA.
DR   PIR; B39741; B39741.
DR   RefSeq; NP_767108.1; NC_004463.1.
DR   RefSeq; WP_011083299.1; NZ_CP011360.1.
DR   AlphaFoldDB; P30964; -.
DR   STRING; 224911.27348716; -.
DR   TCDB; 3.A.1.107.1; the atp-binding cassette (abc) superfamily.
DR   PRIDE; P30964; -.
DR   EnsemblBacteria; BAC45733; BAC45733; BAC45733.
DR   GeneID; 64020327; -.
DR   KEGG; bja:blr0468; -.
DR   PATRIC; fig|224911.44.peg.9001; -.
DR   eggNOG; COG2386; Bacteria.
DR   HOGENOM; CLU_079069_1_0_5; -.
DR   InParanoid; P30964; -.
DR   OMA; VKCLAHW; -.
DR   PhylomeDB; P30964; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR003544; Cyt_c_biogenesis_CcmB.
DR   InterPro; IPR026031; Cyt_c_CcmB_bac.
DR   PANTHER; PTHR30070; PTHR30070; 1.
DR   Pfam; PF03379; CcmB; 1.
DR   PIRSF; PIRSF002764; CcmB; 1.
DR   TIGRFAMs; TIGR01190; ccmB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..222
FT                   /note="Heme exporter protein B"
FT                   /id="PRO_0000201544"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   222 AA;  22668 MW;  88FF8405C9E96685 CRC64;
     MTALSALIRR DIRIALRVGG GALIGVLFFL TVVVLMPFAV GPDLALLSRL GPAILWLGAL
     LASLLTLDRL FMADHEDGSL DLITMSRTPL ELACAAKALA HWLAAGLPLI VATPVLGLLL
     NLDMVATGAV ALTLLAGTPA LTFTGMIGAA LAVTLHRGGL LMAVLVLPLS IPVLIFGVAA
     SQAVIVGPMS FGAPFSILCA LSLVSLVIGP FAAAASLRHG LD