CCMB_RHOCB
ID CCMB_RHOCB Reviewed; 218 AA.
AC P29960; D5AU92;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 31-MAY-2011, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Heme exporter protein B;
DE AltName: Full=Cytochrome c-type biogenesis protein HelB;
GN Name=helB; Synonyms=ccmB; OrderedLocusNames=RCAP_rcc01786;
OS Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Rhodobacteraceae; Rhodobacter.
OX NCBI_TaxID=272942;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=1310666; DOI=10.1101/gad.6.2.268;
RA Beckman D.L., Trawick D.R., Kranz R.G.;
RT "Bacterial cytochromes c biogenesis.";
RL Genes Dev. 6:268-283(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=20418398; DOI=10.1128/jb.00366-10;
RA Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA Haselkorn R.;
RT "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT Rhodobacter capsulatus SB 1003.";
RL J. Bacteriol. 192:3545-3546(2010).
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmB/CycW/HelB family. {ECO:0000305}.
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DR EMBL; X63462; CAA45062.1; -; Genomic_DNA.
DR EMBL; CP001312; ADE85531.1; -; Genomic_DNA.
DR PIR; S23664; S23664.
DR RefSeq; WP_013067510.1; NC_014034.1.
DR AlphaFoldDB; P29960; -.
DR STRING; 272942.RCAP_rcc01786; -.
DR EnsemblBacteria; ADE85531; ADE85531; RCAP_rcc01786.
DR GeneID; 31490661; -.
DR KEGG; rcp:RCAP_rcc01786; -.
DR eggNOG; COG2386; Bacteria.
DR HOGENOM; CLU_079069_1_0_5; -.
DR OMA; VKCLAHW; -.
DR OrthoDB; 1886257at2; -.
DR Proteomes; UP000002361; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR003544; Cyt_c_biogenesis_CcmB.
DR InterPro; IPR026031; Cyt_c_CcmB_bac.
DR PANTHER; PTHR30070; PTHR30070; 1.
DR Pfam; PF03379; CcmB; 1.
DR PIRSF; PIRSF002764; CcmB; 1.
DR TIGRFAMs; TIGR01190; ccmB; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..218
FT /note="Heme exporter protein B"
FT /id="PRO_0000201546"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 160
FT /note="P -> S (in Ref. 1; CAA45062)"
FT /evidence="ECO:0000305"
FT CONFLICT 163
FT /note="A -> V (in Ref. 1; CAA45062)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 218 AA; 22593 MW; ED2396EFD4B744ED CRC64;
MRALLSRDLR LAIRAGGGFG LGLAFFLIVV TLVPFGVGPQ GEILARIASG ILWLGALLAC
LLSLDRIFAL DFEDGSLDLL ATAPIPMEAV VTIKALAHWI TTGLPLVLAA PLFAVLLHLP
APAYLWLEVS LLLGTPALSV LGTFGAALTV GLKRGGLLLP LLALPLYVPT LIFGAELVRR
GAEGLAIEVP LAMLAGITAA TVALVPFASA AAIRVNLR
