ID   CCMC_RHOCB              Reviewed;         242 AA.
AC   P29961; D5AU93;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Heme exporter protein C;
DE   AltName: Full=Cytochrome c-type biogenesis protein HelC;
GN   Name=helC; Synonyms=ccmC; OrderedLocusNames=RCAP_rcc01787;
OS   Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=272942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=1310666; DOI=10.1101/gad.6.2.268;
RA   Beckman D.L., Trawick D.R., Kranz R.G.;
RT   "Bacterial cytochromes c biogenesis.";
RL   Genes Dev. 6:268-283(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=20418398; DOI=10.1128/jb.00366-10;
RA   Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA   Haselkorn R.;
RT   "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT   Rhodobacter capsulatus SB 1003.";
RL   J. Bacteriol. 192:3545-3546(2010).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family. {ECO:0000305}.
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DR   EMBL; X63462; CAA45063.1; -; Genomic_DNA.
DR   EMBL; CP001312; ADE85532.1; -; Genomic_DNA.
DR   PIR; S23665; S23665.
DR   RefSeq; WP_013067511.1; NC_014034.1.
DR   AlphaFoldDB; P29961; -.
DR   SMR; P29961; -.
DR   STRING; 272942.RCAP_rcc01787; -.
DR   TCDB; 9.B.14.2.1; the putative heme handling protein (hhp) family.
DR   EnsemblBacteria; ADE85532; ADE85532; RCAP_rcc01787.
DR   GeneID; 31490662; -.
DR   KEGG; rcp:RCAP_rcc01787; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_066538_2_1_5; -.
DR   OMA; FHVPMWF; -.
DR   OrthoDB; 955123at2; -.
DR   Proteomes; UP000002361; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   PRINTS; PR01386; CCMCBIOGNSIS.
DR   TIGRFAMs; TIGR01191; ccmC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..242
FT                   /note="Heme exporter protein C"
FT                   /id="PRO_0000201560"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   242 AA;  27196 MW;  2966C2BC5160A663 CRC64;
     MSIWEYANPV KFMQTSGRLL PWVVAATVLT LLPGLVWGFF FTPVAAEFGA TVKVIYVHVP
     AATLAINIWV MMLVASLIWL IRRHHVSALA AKAAAPIGMV MTLIALITGA FWGQPMWGTW
     WEWDPRLTSF LILFLFYLGY MALWEAIENP DTAADLTGVL CLVGSVFAVL SRYAAIFWNQ
     GLHQGSTLSL DKEEHIADVY WQPLVLSIAG FGMLFVALLL LRTRTEIRAR RLKALEQRER
     MA