ID   CCMD_ECO57              Reviewed;          69 AA.
AC   P0ABM7; P36770;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Heme exporter protein D;
DE   AltName: Full=Cytochrome c-type biogenesis protein CcmD;
GN   Name=ccmD; OrderedLocusNames=Z3455, ECs3087;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CcmD/CycX/HelD family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG57333.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36510.1; -; Genomic_DNA.
DR   PIR; A85859; A85859.
DR   PIR; G91014; G91014.
DR   RefSeq; NP_311114.1; NC_002695.1.
DR   RefSeq; WP_000186540.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0ABM7; -.
DR   SMR; P0ABM7; -.
DR   STRING; 155864.EDL933_3363; -.
DR   TCDB; 3.A.1.107.3; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAG57333; AAG57333; Z3455.
DR   EnsemblBacteria; BAB36510; BAB36510; ECs_3087.
DR   GeneID; 67416634; -.
DR   GeneID; 916793; -.
DR   KEGG; ece:Z3455; -.
DR   KEGG; ecs:ECs_3087; -.
DR   PATRIC; fig|386585.9.peg.3221; -.
DR   eggNOG; COG3114; Bacteria.
DR   HOGENOM; CLU_180892_0_0_6; -.
DR   OMA; MFFQSWS; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   GO; GO:0015886; P:heme transport; IEA:InterPro.
DR   InterPro; IPR007078; Haem_export_protD_CcmD.
DR   Pfam; PF04995; CcmD; 1.
DR   TIGRFAMs; TIGR03141; cytochro_ccmD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..69
FT                   /note="Heme exporter protein D"
FT                   /id="PRO_0000201564"
FT   TRANSMEM        18..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   69 AA;  7745 MW;  BEC1D341EEADA018 CRC64;
     MTPAFASWNE FFAMGGYAFF VWLAVVMTVI PLVVLVVHSV MQHRAILRGV AQQRAREARL
     RAAQQQEAA