ID   CCMD_ECOL6              Reviewed;          69 AA.
AC   P0ABM6; P36770;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Heme exporter protein D;
DE   AltName: Full=Cytochrome c-type biogenesis protein CcmD;
GN   Name=ccmD; OrderedLocusNames=c2735;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CcmD/CycX/HelD family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN81189.1; -; Genomic_DNA.
DR   RefSeq; WP_000186540.1; NC_004431.1.
DR   AlphaFoldDB; P0ABM6; -.
DR   SMR; P0ABM6; -.
DR   STRING; 199310.c2735; -.
DR   EnsemblBacteria; AAN81189; AAN81189; c2735.
DR   GeneID; 67416634; -.
DR   KEGG; ecc:c2735; -.
DR   eggNOG; COG3114; Bacteria.
DR   HOGENOM; CLU_180892_0_0_6; -.
DR   OMA; MFFQSWS; -.
DR   BioCyc; ECOL199310:C2735-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   GO; GO:0015886; P:heme transport; IEA:InterPro.
DR   InterPro; IPR007078; Haem_export_protD_CcmD.
DR   Pfam; PF04995; CcmD; 1.
DR   TIGRFAMs; TIGR03141; cytochro_ccmD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..69
FT                   /note="Heme exporter protein D"
FT                   /id="PRO_0000201565"
FT   TRANSMEM        18..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   69 AA;  7745 MW;  BEC1D341EEADA018 CRC64;
     MTPAFASWNE FFAMGGYAFF VWLAVVMTVI PLVVLVVHSV MQHRAILRGV AQQRAREARL
     RAAQQQEAA