ID   CCMD_HAEIN              Reviewed;          67 AA.
AC   P45035;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Heme exporter protein D;
DE   AltName: Full=Cytochrome c-type biogenesis protein CcmD;
GN   Name=ccmD; OrderedLocusNames=HI_1092;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CcmD/CycX/HelD family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22749.1; -; Genomic_DNA.
DR   PIR; H64166; H64166.
DR   RefSeq; NP_439249.1; NC_000907.1.
DR   RefSeq; WP_005693416.1; NC_000907.1.
DR   AlphaFoldDB; P45035; -.
DR   SMR; P45035; -.
DR   STRING; 71421.HI_1092; -.
DR   EnsemblBacteria; AAC22749; AAC22749; HI_1092.
DR   KEGG; hin:HI_1092; -.
DR   PATRIC; fig|71421.8.peg.1137; -.
DR   eggNOG; COG3114; Bacteria.
DR   HOGENOM; CLU_180892_0_1_6; -.
DR   OMA; MFFQSWS; -.
DR   PhylomeDB; P45035; -.
DR   BioCyc; HINF71421:G1GJ1-1127-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   GO; GO:0015886; P:heme transport; IEA:InterPro.
DR   InterPro; IPR007078; Haem_export_protD_CcmD.
DR   Pfam; PF04995; CcmD; 1.
DR   TIGRFAMs; TIGR03141; cytochro_ccmD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..67
FT                   /note="Heme exporter protein D"
FT                   /id="PRO_0000201567"
FT   TRANSMEM        17..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   67 AA;  7847 MW;  A6F78561DB5C3114 CRC64;
     MFFQTWSDFF NMGGYGFYVW LSYAVSLVAV IALIVQSVKQ RKTVLQNVLR EKQREERLQQ
     ANKGNTL