CCMF_BRADU
ID CCMF_BRADU Reviewed; 660 AA.
AC P45403;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2003, sequence version 2.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Cytochrome c-type biogenesis protein CycK;
GN Name=cycK; OrderedLocusNames=blr3127;
OS Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS NBRC 14792 / USDA 110).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Bradyrhizobium.
OX NCBI_TaxID=224911;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=USDA 110spc4;
RX PubMed=7715601; DOI=10.1007/bf00425818;
RA Ritz D., Thoeny-Meyer L., Hennecke H.;
RT "The cycHJKL gene cluster plays an essential role in the biogenesis of c-
RT type cytochromes in Bradyrhizobium japonicum.";
RL Mol. Gen. Genet. 247:27-38(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000305}.
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DR EMBL; Z22517; CAA80244.1; -; Genomic_DNA.
DR EMBL; Z46607; CAA86575.1; -; Genomic_DNA.
DR EMBL; BA000040; BAC48392.1; -; Genomic_DNA.
DR PIR; S54746; S54746.
DR RefSeq; NP_769767.1; NC_004463.1.
DR RefSeq; WP_011085911.1; NZ_CP011360.1.
DR AlphaFoldDB; P45403; -.
DR SMR; P45403; -.
DR STRING; 224911.27351385; -.
DR TCDB; 9.B.14.1.2; the putative heme handling protein (hhp) family.
DR EnsemblBacteria; BAC48392; BAC48392; BAC48392.
DR GeneID; 64022879; -.
DR KEGG; bja:blr3127; -.
DR PATRIC; fig|224911.44.peg.2760; -.
DR eggNOG; COG1138; Bacteria.
DR HOGENOM; CLU_015041_3_0_5; -.
DR InParanoid; P45403; -.
DR OMA; SYWGMQL; -.
DR PhylomeDB; P45403; -.
DR Proteomes; UP000002526; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR PANTHER; PTHR43653; PTHR43653; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
DR TIGRFAMs; TIGR00353; nrfE; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..660
FT /note="Cytochrome c-type biogenesis protein CycK"
FT /id="PRO_0000201585"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 419..439
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 617..637
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 205
FT /note="R -> L (in Ref. 1; CAA80244/CAA86575)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 660 AA; 71127 MW; 15B685136CA6D741 CRC64;
MIAESGHYAL VLALGLALIQ SIVPLIGARL RDDALMSVAR STALAQLLFV GASFVALVML
HVNSDFSVAN VYENSHSMKP LLYKITGVWG NHEGSMLLWV SILALFGGLV AAFGNNLPLS
LRAHVLAVQA WIASAFYLFI LVTSNPFLRI ANPPIEGRDL NPVLQDIGLA VHPPMLYLGY
VGFSISFSFA IAALMEGRID AAWARWVRPW TLVAWIFLTL GIAMGSYWAY YELGWGGWWF
WDPVENASLM PWLAGTALLH SALVMEKRNA LKVWTILLSI LTFSLSLLGT FLVRSGVITS
VHAFATDPTR GVFILLILCL FIGGSLSLFA GRATSLKQGG LFAPISREGA LVLNNLLLTV
ACAVVLFGTL YPLAMEMLAD FKMSVGAPFY NLTFAPLFAL LLLAVPFGPM LAWKRGDLLG
VTQRLLAAGV AGLVVVAIVW AWTRGGSALA PLAIGLGVFV IAGAVTDLVE RTGLVRLPLA
TALQRARGLP RSAWGAALAH AGLGVALIGI VCETTWNSEY IATMKRSDVA HVAGYDVKLD
GLFQRQGPNY REMIAEFNVS RDGETLSVMT PSKRSFTTRG SSTTEAALLT RGASQLYISL
GDANAEGAIA VRIYHKPLVL LIWWGPVLMA FGGVLSLSDR RLRVGAPKPA RAKQRLQPAE
