CCMF_PSEAE
ID CCMF_PSEAE Reviewed; 657 AA.
AC Q9I3N2;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Cytochrome c-type biogenesis protein CcmF;
GN Name=ccmF; OrderedLocusNames=PA1480;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000305}.
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DR EMBL; AE004091; AAG04869.1; -; Genomic_DNA.
DR PIR; A83460; A83460.
DR RefSeq; NP_250171.1; NC_002516.2.
DR RefSeq; WP_003114291.1; NZ_QZGE01000005.1.
DR AlphaFoldDB; Q9I3N2; -.
DR SMR; Q9I3N2; -.
DR STRING; 287.DR97_543; -.
DR TCDB; 9.B.14.1.7; the putative heme handling protein (hhp) family.
DR PaxDb; Q9I3N2; -.
DR PRIDE; Q9I3N2; -.
DR EnsemblBacteria; AAG04869; AAG04869; PA1480.
DR GeneID; 881004; -.
DR KEGG; pae:PA1480; -.
DR PATRIC; fig|208964.12.peg.1531; -.
DR PseudoCAP; PA1480; -.
DR HOGENOM; CLU_015041_3_0_6; -.
DR InParanoid; Q9I3N2; -.
DR OMA; SYWGMQL; -.
DR PhylomeDB; Q9I3N2; -.
DR BioCyc; PAER208964:G1FZ6-1506-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004096; F:catalase activity; IMP:PseudoCAP.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:PseudoCAP.
DR GO; GO:0071977; P:bacterial-type flagellum-dependent swimming motility; IMP:PseudoCAP.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR GO; GO:0002049; P:pyoverdine biosynthetic process; IMP:PseudoCAP.
DR GO; GO:0043107; P:type IV pilus-dependent motility; IMP:PseudoCAP.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR PANTHER; PTHR43653; PTHR43653; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
DR TIGRFAMs; TIGR00353; nrfE; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..657
FT /note="Cytochrome c-type biogenesis protein CcmF"
FT /id="PRO_0000287764"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 614..634
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 657 AA; 71666 MW; B91E0B463C703833 CRC64;
MIPELGHLAL ILALCLALVQ SSLPLVGAWR GDRQWMSLAR PAAWGQFAFL AFAFGCLTWA
FLRDDFSVAY VAGNSNSALP WYYKFSAVWG AHEGSLLLWA LILGGWTFAV SIFSRQLPEV
MLARVLAVMG MISTGFLLFL IITSNPFSRL LPQTPMDGND LNPLLQDVGL IVHPPMLYMG
YVGFSVAFAF AIAALLGGRL DAAWARWSRP WTLVAWAFLG IGIVLGSWWA YYELGWGGWW
FWDPVENASF MPWLVGTALI HSLAVTEKRG VFKSWTVLLA IAAFSLSLLG TFLVRSGVLT
SVHAFASDPE RGVFILAFLL LVVGGSLTLF ALRAPVVKSQ VGFALWSRET LLLLNNLVLV
VAASMILLGT LYPLLLDALS GAKLSVGPPY FNAMFLPLMA ALMAALAVGV LVRWKDTPSR
WLLGMLTPVL AASAVLAAAG SMYFGDFNWA VLAVFLLSAW VVLAGFRDFL DKTRHKGVLA
GARSLTRSYW GMQLAHLGIA VCAIGIVLSS QYSAQRDLRM SPGDTVELGG YHFLFDGAKH
HEGPNYTSDK GSIHVSRDGK EIATLHPEKR LYTVQSSMMT EAGIDAGFTR DLYVALGEPL
ENGAWAVRVH VKPFVRWIWF GGLLMGLGGA LAALDRRYRV KVKTRVREAL GLAGQGA
