CCMF_RHIME
ID CCMF_RHIME Reviewed; 676 AA.
AC P45404;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Cytochrome c-type biogenesis protein CycK;
GN Name=cycK; OrderedLocusNames=R01019; ORFNames=SMc02363;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=AK631;
RX PubMed=7715602; DOI=10.1007/bf00425819;
RA Kereszt A., Slaska-Kiss K., Putnoky P., Banfalvi Z., Kondorosi A.;
RT "The cycHJKL genes of Rhizobium meliloti involved in cytochrome c
RT biogenesis are required for 'respiratory' nitrate reduction ex planta and
RT for nitrogen fixation during symbiosis.";
RL Mol. Gen. Genet. 247:39-47(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X82560; CAA57906.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45591.1; -; Genomic_DNA.
DR PIR; S54750; S54750.
DR RefSeq; NP_385125.1; NC_003047.1.
DR RefSeq; WP_010968989.1; NC_003047.1.
DR AlphaFoldDB; P45404; -.
DR SMR; P45404; -.
DR STRING; 266834.SMc02363; -.
DR PRIDE; P45404; -.
DR EnsemblBacteria; CAC45591; CAC45591; SMc02363.
DR GeneID; 61602484; -.
DR KEGG; sme:SMc02363; -.
DR PATRIC; fig|266834.11.peg.2423; -.
DR eggNOG; COG1138; Bacteria.
DR HOGENOM; CLU_015041_3_0_5; -.
DR OMA; SYWGMQL; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR PANTHER; PTHR43653; PTHR43653; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
DR TIGRFAMs; TIGR00353; nrfE; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Cytochrome c-type biogenesis; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..676
FT /note="Cytochrome c-type biogenesis protein CycK"
FT /id="PRO_0000201587"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 617..637
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 319
FT /note="V -> I (in Ref. 1; CAA57906)"
FT /evidence="ECO:0000305"
FT CONFLICT 658
FT /note="H -> R (in Ref. 1; CAA57906)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 676 AA; 72611 MW; A2DD652280895E0D CRC64;
MIIELGHYAL VLALATAIIQ GVLPVLGVRR GDPSLMGLAA NAALVCFLLV AFSFAVLTFA
YVTSDFSVKN VWENSHSLKP LIYKITGVWG NHEGSMLLWL LILVFFSAMV ALFGRNLPET
LKANVLAVQA WIATAFAFFV LLTSNPFARL VPAPGEGRDL NPVLQDIGLA IHPPLLYLGY
VGFSVCFSFA VAALIEGRID AAWARWVRPW TLAAWTFLTA GIAMGSYWAY YELGWGGWWF
WDPVENASFM PWLAGTALLH SALVMEKREA LKIWTVLLAI MTFSLSLLGT FLVRSGVLTS
VHAFATDPTR GVFILAILVV FIGGAFSLFA FRASHLKAGG IFAPVSREGA LVVNNLILTT
ATATVLTGTL YPLVLEALTG DKISVGAPFF NMTFGLLMLP LIAVVPFGPL LAWKRGDLAG
AAQRLFAAAA LGLLAAAICY YAVNGGPVLA PFGLGLGVYL ILGALTDLVL RSGLGKVAAG
VAWRRLSGLP RSAFGTALAH IGLGITLIGI VTVTAFETET VVEMKPGAVV DVGRYSLRFD
GMREGRGPNY TEDAGHFTVS RGGVEVTEIW SSKRLYSARR MPTTEAGIRT FGLSQLYVSL
GDDMADGGIV VRIWWKPLIL CIWGGALVMM AGGVVSLSDR RLRVGAPARA RKALALDHDD
FRSDRPKIIN VIDSKG
