CCMH_BRADU
ID CCMH_BRADU Reviewed; 160 AA.
AC P45405;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2003, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Cytochrome c-type biogenesis protein CcmH;
DE AltName: Full=Cytochrome c-type biogenesis protein CycL;
DE Flags: Precursor;
GN Name=ccmH; Synonyms=cycL; OrderedLocusNames=blr3128;
OS Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS NBRC 14792 / USDA 110).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Bradyrhizobium.
OX NCBI_TaxID=224911;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=USDA 110spc4;
RX PubMed=7715601; DOI=10.1007/bf00425818;
RA Ritz D., Thoeny-Meyer L., Hennecke H.;
RT "The cycHJKL gene cluster plays an essential role in the biogenesis of c-
RT type cytochromes in Bradyrhizobium japonicum.";
RL Mol. Gen. Genet. 247:27-38(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmH/CycL/Ccl2/NrfF family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z22517; CAA80245.1; -; Genomic_DNA.
DR EMBL; Z46607; CAA86576.1; -; Genomic_DNA.
DR EMBL; BA000040; BAC48393.1; -; Genomic_DNA.
DR PIR; S54747; S54747.
DR RefSeq; NP_769768.1; NC_004463.1.
DR RefSeq; WP_011085912.1; NZ_CP011360.1.
DR AlphaFoldDB; P45405; -.
DR SMR; P45405; -.
DR STRING; 224911.27351386; -.
DR EnsemblBacteria; BAC48393; BAC48393; BAC48393.
DR GeneID; 64022880; -.
DR KEGG; bja:blr3128; -.
DR PATRIC; fig|224911.44.peg.2761; -.
DR eggNOG; COG3088; Bacteria.
DR HOGENOM; CLU_107187_2_0_5; -.
DR InParanoid; P45405; -.
DR OMA; MIAADMR; -.
DR PhylomeDB; P45405; -.
DR Proteomes; UP000002526; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.640; -; 1.
DR InterPro; IPR005616; CcmH/CycL/Ccl2/NrfF.
DR InterPro; IPR038297; CcmH/CycL/NrfF/Ccl2_sf.
DR Pfam; PF03918; CcmH; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis; Heme; Iron; Membrane; Metal-binding;
KW Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..160
FT /note="Cytochrome c-type biogenesis protein CcmH"
FT /id="PRO_0000006608"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT BINDING 46
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT /evidence="ECO:0000255"
FT BINDING 49
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT /evidence="ECO:0000255"
FT CONFLICT 75
FT /note="A -> G (in Ref. 1; CAA80245/CAA86576)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 160 AA; 17736 MW; 470923579C6CCCED CRC64;
MRRMMAAFVA LALLASPAVH AVQPDEIMSD PAKETRARDL SRELRCMVCQ NQSIDDSDAP
LARDLRLLVR ERIAAGDSNS QVLDFLVARY GEFVLLKPRF ERQTLLLWLL GPLLLTGGGL
ALWLQIRRRS RSGADLPAPP LTPDEEARLA ALMSDEAKSS
