CCMH_PSEFL
ID CCMH_PSEFL Reviewed; 156 AA.
AC P52226;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Cytochrome c-type biogenesis protein CcmH;
DE AltName: Full=Cytochrome c-type biogenesis protein CycL;
DE Flags: Precursor;
GN Name=ccmH; Synonyms=cycL;
OS Pseudomonas fluorescens.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=294;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=09906;
RA Yang C.H., Azad H.R., Cooksey D.A.;
RL Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CcmH/CycL/Ccl2/NrfF family. {ECO:0000305}.
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DR EMBL; U44827; AAC44228.1; -; Genomic_DNA.
DR AlphaFoldDB; P52226; -.
DR SMR; P52226; -.
DR STRING; 690597.JH730938_gene2123; -.
DR eggNOG; COG3088; Bacteria.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.640; -; 1.
DR InterPro; IPR005616; CcmH/CycL/Ccl2/NrfF.
DR InterPro; IPR038297; CcmH/CycL/NrfF/Ccl2_sf.
DR Pfam; PF03918; CcmH; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis; Heme; Iron; Membrane; Metal-binding; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..156
FT /note="Cytochrome c-type biogenesis protein CcmH"
FT /id="PRO_0000006609"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 131..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 44
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT /evidence="ECO:0000255"
FT BINDING 47
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /note="covalent"
FT /evidence="ECO:0000255"
SQ SEQUENCE 156 AA; 17470 MW; 99F343A16FE3338A CRC64;
MKRLLAAAVC LGPGRCGHAA IDTYEFANDA ERERFRDLTK ELRCPKCQNQ DIADSNAPIA
TDLRREIFRM LGEGKDDQQI IDFMVDRYGD FVRYKPALTG KTALLWFGPA GLLLAGVVVM
AVIVRRRRAA PTDGSDALSP EERKRLDQLL DTKTDD