ID   CCMK3_HALP7             Reviewed;         102 AA.
AC   K9Y7V9;
DT   07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Carboxysome shell protein CcmK3 {ECO:0000303|PubMed:30389783};
DE   AltName: Full=Carbon dioxide-concentrating mechanism protein CcmK3 {ECO:0000255|HAMAP-Rule:MF_00854};
GN   Name=ccmK3 {ECO:0000303|PubMed:30389783}; OrderedLocusNames=PCC7418_0348;
OS   Halothece sp. (strain PCC 7418) (Synechococcus sp. (strain PCC 7418)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Halothece cluster; Halothece; unclassified Halothece.
OX   NCBI_TaxID=65093;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7418;
RX   PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA   Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA   Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA   Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA   Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT   "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT   genome sequencing.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
RN   [2]
RP   FUNCTION, SUBCELLULAR LOCATION, AND SUBUNIT.
RC   STRAIN=PCC 7418;
RX   PubMed=30389783; DOI=10.1104/pp.18.01190;
RA   Sommer M., Sutter M., Gupta S., Kirst H., Turmo A., Lechno-Yossef S.,
RA   Burton R.L., Saechao C., Sloan N.B., Cheng X., Chan L.G., Petzold C.J.,
RA   Fuentes-Cabrera M., Ralston C.Y., Kerfeld C.A.;
RT   "Heterohexamers Formed by CcmK3 and CcmK4 Increase the Complexity of Beta
RT   Carboxysome Shells.";
RL   Plant Physiol. 179:156-167(2019).
CC   -!- FUNCTION: A probably non-essential, minor shell protein of the
CC       carboxysome, a polyhedral inclusion where RuBisCO (ribulose
CC       bisphosphate carboxylase, rbcL-rbcS) is sequestered. Hexamers form
CC       sheets that form the facets of the polyhedral carboxysome. In PCC 7418
CC       there are several CcmK paralogs with presumably functional differences.
CC       This subunit probably only makes heterohexamers with CcmK4.
CC       Heterohexamers can also make dodecamers, formation depends on buffer
CC       conditions. {ECO:0000269|PubMed:30389783}.
CC   -!- SUBUNIT: Interacts stably with CcmK4, forming heterohexamers that can
CC       make dodecamers. Heterohexamers have a 1:2 CcmK3:CcmK4 stoichiometry.
CC       Upon expression in E.coli forms oligomers that could be dimers or
CC       trimers, but never hexamers; bulky residues in the pore region probably
CC       preclude the formation of homohexamers. {ECO:0000269|PubMed:30389783}.
CC   -!- SUBCELLULAR LOCATION: Carboxysome {ECO:0000255|HAMAP-Rule:MF_00854,
CC       ECO:0000305|PubMed:30389783}. Note=This cyanobacterium makes beta-type
CC       carboxysomes. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC       CcmK subfamily. {ECO:0000255|HAMAP-Rule:MF_00854}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003945; AFZ42582.1; -; Genomic_DNA.
DR   RefSeq; WP_015224460.1; NC_019779.1.
DR   AlphaFoldDB; K9Y7V9; -.
DR   SMR; K9Y7V9; -.
DR   STRING; 65093.PCC7418_0348; -.
DR   EnsemblBacteria; AFZ42582; AFZ42582; PCC7418_0348.
DR   KEGG; hao:PCC7418_0348; -.
DR   PATRIC; fig|65093.3.peg.364; -.
DR   eggNOG; COG4577; Bacteria.
DR   HOGENOM; CLU_064903_5_0_3; -.
DR   OMA; ITHYIVP; -.
DR   OrthoDB; 1802372at2; -.
DR   Proteomes; UP000010481; Chromosome.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProtKB-SubCell.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1710; -; 1.
DR   HAMAP; MF_00854; CcmK; 1.
DR   InterPro; IPR020808; Bact_microcomp_CS.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR046380; CcmK.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR044872; CcmK/CsoS1_BMC.
DR   Pfam; PF00936; BMC; 1.
DR   SMART; SM00877; BMC; 1.
DR   SUPFAM; SSF143414; SSF143414; 1.
DR   PROSITE; PS01139; BMC_1; 1.
DR   PROSITE; PS51930; BMC_2; 1.
PE   1: Evidence at protein level;
KW   Bacterial microcompartment; Carbon dioxide fixation; Carboxysome;
KW   Photosynthesis; Reference proteome.
FT   CHAIN           1..102
FT                   /note="Carboxysome shell protein CcmK3"
FT                   /id="PRO_0000451237"
FT   DOMAIN          4..90
FT                   /note="BMC"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00854"
SQ   SEQUENCE   102 AA;  10889 MW;  41A401085AE2CF0B CRC64;
     MPVAVGVIQT DGFPAVLAAA DAMVKAASVT LVSFDKAERA QFYVAVRGPV SEVERSMEAG
     IAAAEETYNG TVITHYMIPN PPDNVETVMP IAYSDEVEPF RV