ID   CCMK_SYNP2              Reviewed;         112 AA.
AC   O30709; B1XQ08;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Carboxysome shell protein CcmK {ECO:0000255|HAMAP-Rule:MF_00854};
DE   AltName: Full=Carbon dioxide-concentrating mechanism protein CcmK {ECO:0000255|HAMAP-Rule:MF_00854};
GN   Name=ccmK {ECO:0000255|HAMAP-Rule:MF_00854, ECO:0000303|Ref.1};
GN   OrderedLocusNames=SYNPCC7002_A1802;
OS   Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum
OS   quadruplicatum).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RX   DOI=10.1046/j.1529-8817.2000.00028.x;
RA   Ludwig M., Sultemeyer D., Price G.D.;
RT   "Isolation of ccmKLMN genes from the marine cyanobacterium, Synechococcus
RT   sp. PCC7002 (Cyanophyceae), and evidence that CcmM is essential for
RT   carboxysome assembly.";
RL   J. Phycol. 36:1109-1118(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RA   Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T.,
RA   Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J.,
RA   Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.;
RT   "Complete sequence of Synechococcus sp. PCC 7002.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: One of the shell proteins of the carboxysome, a polyhedral
CC       inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS)
CC       is sequestered. Assembles into hexamers which make sheets that form the
CC       facets of the polyhedral carboxysome. The hexamer central pore probably
CC       regulates metabolite flux. {ECO:0000255|HAMAP-Rule:MF_00854}.
CC   -!- SUBUNIT: Homohexamer. Interacts with CcmN and CcmO in the carboxysome.
CC       {ECO:0000255|HAMAP-Rule:MF_00854}.
CC   -!- SUBCELLULAR LOCATION: Carboxysome {ECO:0000255|HAMAP-Rule:MF_00854,
CC       ECO:0000305|Ref.1}. Note=This cyanobacterium makes beta-type
CC       carboxysomes. {ECO:0000305}.
CC   -!- DOMAIN: The tight homohexamer forms a small pore which is positively
CC       charged. {ECO:0000255|HAMAP-Rule:MF_00854}.
CC   -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC       CcmK subfamily. {ECO:0000255|HAMAP-Rule:MF_00854}.
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DR   EMBL; AF015889; AAB66835.1; -; Genomic_DNA.
DR   EMBL; CP000951; ACA99790.1; -; Genomic_DNA.
DR   RefSeq; WP_012307413.1; NC_010475.1.
DR   AlphaFoldDB; O30709; -.
DR   SMR; O30709; -.
DR   STRING; 32049.SYNPCC7002_A1802; -.
DR   EnsemblBacteria; ACA99790; ACA99790; SYNPCC7002_A1802.
DR   KEGG; syp:SYNPCC7002_A1802; -.
DR   eggNOG; COG4577; Bacteria.
DR   HOGENOM; CLU_064903_5_0_3; -.
DR   OMA; QFREGVN; -.
DR   Proteomes; UP000001688; Chromosome.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProtKB-SubCell.
DR   GO; GO:0043886; F:structural constituent of carboxysome; IEA:UniProt.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1710; -; 1.
DR   HAMAP; MF_00854; CcmK; 1.
DR   InterPro; IPR020808; Bact_microcomp_CS.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR046380; CcmK.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR044872; CcmK/CsoS1_BMC.
DR   Pfam; PF00936; BMC; 1.
DR   SMART; SM00877; BMC; 1.
DR   SUPFAM; SSF143414; SSF143414; 1.
DR   PROSITE; PS01139; BMC_1; 1.
DR   PROSITE; PS51930; BMC_2; 1.
PE   3: Inferred from homology;
KW   Bacterial microcompartment; Carbon dioxide fixation; Carboxysome;
KW   Photosynthesis; Reference proteome.
FT   CHAIN           1..112
FT                   /note="Carboxysome shell protein CcmK"
FT                   /id="PRO_0000201502"
FT   DOMAIN          4..90
FT                   /note="BMC"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00854"
FT   CONFLICT        2
FT                   /note="S -> P (in Ref. 1; AAB66835)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        8
FT                   /note="V -> I (in Ref. 1; AAB66835)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        11
FT                   /note="L -> R (in Ref. 1; AAB66835)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   112 AA;  12033 MW;  AA5606657F41B0AC CRC64;
     MSIAVGMVET LGFPAVVEAA DAMVKAARVT LVGYEKIGSG RVTVIVRGDV SEVQASVSAG
     TDNVSRVNGG QVLSTHIIAR PHENLEYVLP IRYTEAVEQF RESVNPQPLR RV