CCML_GLOVI
ID CCML_GLOVI Reviewed; 100 AA.
AC Q7NIT8;
DT 07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Carboxysome shell vertex protein CcmL {ECO:0000255|HAMAP-Rule:MF_00858};
DE AltName: Full=Carbon dioxide concentrating mechanism protein CcmL {ECO:0000255|HAMAP-Rule:MF_00858};
GN Name=ccmL {ECO:0000255|HAMAP-Rule:MF_00858};
GN Synonyms=gvip287 {ECO:0000303|PubMed:23949415}; OrderedLocusNames=gll2094;
OS Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC Gloeobacter.
OX NCBI_TaxID=251221;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29082 / PCC 7421;
RX PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA Tabata S.;
RT "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT cyanobacterium that lacks thylakoids.";
RL DNA Res. 10:137-145(2003).
RN [2] {ECO:0007744|PDB:4JW0}
RP X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS), SUBUNIT, AND DOMAIN.
RC STRAIN=ATCC 29082 / PCC 7421;
RX PubMed=23949415; DOI=10.1007/s11120-013-9909-z;
RA Sutter M., Wilson S.C., Deutsch S., Kerfeld C.A.;
RT "Two new high-resolution crystal structures of carboxysome pentamer
RT proteins reveal high structural conservation of CcmL orthologs among
RT distantly related cyanobacterial species.";
RL Photosyn. Res. 118:9-16(2013).
CC -!- FUNCTION: Probably forms vertices in the carboxysome, a polyhedral
CC inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS)
CC is sequestered. Has been modeled to induce curvature upon insertion
CC into an otherwise flat hexagonal molecular layer of CcmK subunits.
CC {ECO:0000250|UniProtKB:P72759, ECO:0000255|HAMAP-Rule:MF_00858}.
CC -!- SUBUNIT: Homopentamer (PubMed:23949415). Interacts with full-length
CC CcmM (By similarity). {ECO:0000250|UniProtKB:P72759,
CC ECO:0000269|PubMed:23949415}.
CC -!- SUBCELLULAR LOCATION: Carboxysome {ECO:0000250|UniProtKB:Q03512,
CC ECO:0000255|HAMAP-Rule:MF_00858}. Note=Probably forms vertices in the
CC carboxysome. {ECO:0000305|PubMed:23949415}.
CC -!- DOMAIN: The tight homopentamer forms a pore with an opening of about 4
CC Angstroms in diameter which opens into a wider tunnel at the base of
CC the truncated pyramid. The pore is positively charged.
CC {ECO:0000269|PubMed:23949415}.
CC -!- SIMILARITY: Belongs to the CcmL/EutN family. CcmL subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_00858}.
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DR EMBL; BA000045; BAC90035.1; -; Genomic_DNA.
DR RefSeq; NP_925040.1; NC_005125.1.
DR RefSeq; WP_011142092.1; NC_005125.1.
DR PDB; 4JW0; X-ray; 1.70 A; A/B/C/D/E=1-100.
DR PDBsum; 4JW0; -.
DR AlphaFoldDB; Q7NIT8; -.
DR SMR; Q7NIT8; -.
DR STRING; 251221.35212661; -.
DR EnsemblBacteria; BAC90035; BAC90035; BAC90035.
DR KEGG; gvi:gll2094; -.
DR PATRIC; fig|251221.4.peg.2129; -.
DR eggNOG; COG4576; Bacteria.
DR HOGENOM; CLU_148498_0_1_3; -.
DR InParanoid; Q7NIT8; -.
DR OMA; GAGINEW; -.
DR OrthoDB; 1832681at2; -.
DR PhylomeDB; Q7NIT8; -.
DR Proteomes; UP000000557; Chromosome.
DR GO; GO:0031470; C:carboxysome; IEA:UniProtKB-SubCell.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR CDD; cd01614; EutN_CcmL; 1.
DR Gene3D; 2.40.50.220; -; 1.
DR HAMAP; MF_00858; CcmL; 1.
DR InterPro; IPR046387; CcmL.
DR InterPro; IPR004992; EutN_CcmL.
DR InterPro; IPR036677; EutN_CcmL_sf.
DR PANTHER; PTHR36539; PTHR36539; 1.
DR Pfam; PF03319; EutN_CcmL; 1.
DR SUPFAM; SSF159133; SSF159133; 1.
DR PROSITE; PS51932; BMV; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial microcompartment; Carbon dioxide fixation;
KW Carboxysome; Photosynthesis; Reference proteome.
FT CHAIN 1..100
FT /note="Carboxysome shell vertex protein CcmL"
FT /id="PRO_0000451289"
FT DOMAIN 1..83
FT /note="BMV"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00858"
FT STRAND 2..11
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 13..15
FT /evidence="ECO:0007829|PDB:4JW0"
FT HELIX 17..19
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 24..30
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 36..44
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 54..59
FT /evidence="ECO:0007829|PDB:4JW0"
FT HELIX 60..64
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 76..81
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 84..87
FT /evidence="ECO:0007829|PDB:4JW0"
FT STRAND 90..94
FT /evidence="ECO:0007829|PDB:4JW0"
SQ SEQUENCE 100 AA; 10829 MW; F72AC788C1BB6C81 CRC64;
MQIGRVRGTV VSSQKEPSMV GVKFLLLQLI DEAGQPLPQY EVAADGVGAG LDEWVLFSRG
SAARQVAGSE KRPVDAVVIG IIDTVSVDNR PLYSKKDQYR
