ID   CCMO_SYNP6              Reviewed;         276 AA.
AC   P23656; P23655; Q5N5U7;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Carboxysome assembly protein CcmO {ECO:0000305};
DE   AltName: Full=Carbon dioxide concentrating mechanism protein CcmO;
GN   Name=ccmO; OrderedLocusNames=syc0131_c;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Shinozaki K., Sugiura M.;
RT   "Genes for the large and small subunits of ribulose-1,5-bisphosphate
RT   carboxylase/oxygenase constitute a single operon in a cyanobacterium
RT   Anacystis nidulans 6301.";
RL   Mol. Gen. Genet. 200:27-32(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Required for formation of the carboxysome, a polyhedral
CC       inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS)
CC       is sequestered. Required for recruitment of major shell protein CcmK2
CC       to the pre-carboxysome. Suggested to be a carboxysome shell protein.
CC       {ECO:0000250|UniProtKB:P46205}.
CC   -!- SUBUNIT: Homooligomerizes, possibly as a trimer, interacts with CcmK in
CC       the carboxysome. {ECO:0000250|UniProtKB:P46205}.
CC   -!- SUBCELLULAR LOCATION: Carboxysome {ECO:0000250|UniProtKB:P46205}.
CC       Note=This cyanobacterium makes beta-type carboxysomes. {ECO:0000305}.
CC   -!- DOMAIN: Has 2 BMC domains, is thought to trimerize giving a hexamer
CC       that may interact with CcmK proteins in the carboxysome shell.
CC       {ECO:0000250|UniProtKB:P46205}.
CC   -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01278}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA26970.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=CAA26971.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X03220; CAA26970.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; X03220; CAA26971.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AP008231; BAD78321.1; -; Genomic_DNA.
DR   PIR; S07310; S07310.
DR   RefSeq; WP_011242445.1; NC_006576.1.
DR   AlphaFoldDB; P23656; -.
DR   SMR; P23656; -.
DR   STRING; 269084.syc0131_c; -.
DR   EnsemblBacteria; BAD78321; BAD78321; syc0131_c.
DR   KEGG; syc:syc0131_c; -.
DR   eggNOG; COG4577; Bacteria.
DR   OMA; CTAIVRG; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProtKB-SubCell.
DR   GO; GO:0043886; F:structural constituent of carboxysome; IEA:UniProt.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1710; -; 2.
DR   InterPro; IPR020808; Bact_microcomp_CS.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR044872; CcmK/CsoS1_BMC.
DR   Pfam; PF00936; BMC; 2.
DR   SMART; SM00877; BMC; 2.
DR   SUPFAM; SSF143414; SSF143414; 2.
DR   PROSITE; PS01139; BMC_1; 2.
DR   PROSITE; PS51930; BMC_2; 2.
PE   3: Inferred from homology;
KW   Bacterial microcompartment; Carbon dioxide fixation; Carboxysome;
KW   Photosynthesis; Repeat.
FT   CHAIN           1..276
FT                   /note="Carboxysome assembly protein CcmO"
FT                   /id="PRO_0000004788"
FT   DOMAIN          16..100
FT                   /note="BMC 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01278"
FT   DOMAIN          120..204
FT                   /note="BMC 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01278"
FT   REGION          200..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          252..276
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        81
FT                   /note="Q -> T (in Ref. 1; CAA26970)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   276 AA;  29431 MW;  F25514DB099D931F CRC64;
     MSASLPAYSQ PRNAGALGVI CTRSFPAVVG TADMMLKSAD VTLIGYEKTG SGFCTAIIRG
     GYADIKLALE AGVATARQFE QYVSSTILPR PQGNLEAVLP ISRRLSQEAM ATRSHQNVGA
     IGLIETNGFP ALVGAADAML KSANVKLICY EKTGSGLCTA IVQGTVSNVT VAVEAGMYAA
     ERIGQLNAIM VIPRPLDDLM DSLPEPQSDS EAAQPLQLPL RVREKQPLLE LPELERQPIA
     IEAPRLLAEE RQSALELAQE TPLAEPLELP NPRDDQ