ID   CCN2_ANTMA              Reviewed;         441 AA.
AC   P34801;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=G2/mitotic-specific cyclin-2;
OS   Antirrhinum majus (Garden snapdragon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Plantaginaceae; Antirrhineae; Antirrhinum.
OX   NCBI_TaxID=4151;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8313906; DOI=10.1002/j.1460-2075.1994.tb06299.x;
RA   Fobert P.R., Coen E.S., Murphy G.J.P., Doonan J.H.;
RT   "Patterns of cell division revealed by transcriptional regulation of genes
RT   during the cell cycle in plants.";
RL   EMBO J. 13:616-624(1994).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition. G2/M cyclins accumulate steadily during G2 and
CC       are abruptly destroyed at mitosis.
CC   -!- SUBUNIT: Interacts with the CDC2 and CDK2 protein kinases to form a
CC       serine/threonine kinase holoenzyme complex. The cyclin subunit imparts
CC       substrate specificity to the complex.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X76123; CAA53729.1; -; mRNA.
DR   PIR; S41710; S41710.
DR   AlphaFoldDB; P34801; -.
DR   SMR; P34801; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           1..441
FT                   /note="G2/mitotic-specific cyclin-2"
FT                   /id="PRO_0000080390"
SQ   SEQUENCE   441 AA;  49205 MW;  E6E4C037C98880A7 CRC64;
     MGSRHQVVQQ QNRGDVVPGA IKQKSMAVEK KNRRALGDIG NVVTVRGVEG KALPQVSRPI
     TRGFCAQLIA NAEAAAAENN KNSLAVNAKG ADGALPIKRA VARVPVQKKT VKSKPQEIIE
     ISPDTEKKKA PVLEKEITGE KSLKKKAPTL TSTLTARSKA ASVVRTKPKE QIVDIDAADV
     NNDLAVVEYV EDMYKFYKSA ENDSRPHDYM DSQPEINEKM RAILIDWLVQ VHYKFELSPE
     TLYLTINIVD RYLASKTTSR RELQLLGMSS MLIASKYEEI WAPEVNDLVC ISDGSYSNEQ
     VLRMEKKILG ALEWYLTVPT PYVFLVRFIK ASLPDSDVEK NMVYFLAELG MMNYATIIMY
     CPSMIAAAAV YAARCTLNKM PIWNETLRMH TGFSEVQLMD CAKLLIDFHG GSTDQKLQGI
     YRKYSRLEKG AVALLPQPLL A