ID   CCNA_HYDVD              Reviewed;         420 AA.
AC   P51986;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=G2/mitotic-specific cyclin-A;
DE   Flags: Fragment;
OS   Hydra viridissima (Green hydra) (Chlorohydra viridissima).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6082;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8743953; DOI=10.1242/jcs.109.5.1063;
RA   Scheurlen-Blchle I., Hoffmeister S., Herrmans-Borgmeyer I., Schaller H.C.;
RT   "Presence and expression of G2 cyclins in the coelenterate hydra.";
RL   J. Cell Sci. 109:1063-1069(1996).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition. Interacts with the CDC2 and CDK2 protein kinases
CC       to form MPF. G2/M cyclins accumulate steadily during G2 and are
CC       abruptly destroyed at mitosis (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X90983; CAA62470.1; -; mRNA.
DR   AlphaFoldDB; P51986; -.
DR   SMR; P51986; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           <1..420
FT                   /note="G2/mitotic-specific cyclin-A"
FT                   /id="PRO_0000080344"
FT   REGION          64..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   420 AA;  47989 MW;  79225BF8D1B44788 CRC64;
     LFFQKKYFLD KQLNQNAIQI YQDNLTNQNN NIGKKAKLED EKHAHNKSIT SKYKRVPLAS
     ISNVQGSRIQ PTRAAKEKLK PPQNISDSQL VNDSLKSSNS IQAHNTKNDL HKENLYNESA
     LDTFKESPMV FSPFLSDSSC KKYSSLNGIQ DIDSKLHEVF ELPEYAQDIH NYLKKSEAKY
     RPKSNYMRKQ TDINSSMRAI LIDWLVEVSE EYKLIPQTLY LSVSYIDRFL SHMSVLRGKL
     QLVGAACMLV AAKFEEIYPP EVAEFVYITD DTYTAKQVLR MEHLILKTLA FDLSVPTCRD
     FLSRYLFAAN AKPESQLKYL AEYLSELTLI NCDISVKYAP SMIAASSICV ANHMLNSIPW
     TPTLEFYSGY NIQDLRSCLN EIHLLHLAAS TNPQQAIQQK YKSPKFGCVS SLVPLEMPCF