ID   CCNA_PATVU              Reviewed;         426 AA.
AC   P24861;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=G2/mitotic-specific cyclin-A;
OS   Patella vulgata (Common limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Patelloidea; Patellidae; Patella.
OX   NCBI_TaxID=6465;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Oocyte;
RX   PubMed=1655419;
RA   van Loon A.E., Colas P., Goedemans H.J., Neant I., Dalbon P., Guerrier P.;
RT   "The role of cyclins in the maturation of Patella vulgata oocytes.";
RL   EMBO J. 10:3343-3349(1991).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition. Interacts with the CDC2 and CDK2 protein kinases
CC       to form MPF. G2/M cyclins accumulate steadily during G2 and are
CC       abruptly destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X58357; CAA41254.1; -; mRNA.
DR   PIR; S17792; S17792.
DR   AlphaFoldDB; P24861; -.
DR   SMR; P24861; -.
DR   PRIDE; P24861; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR032447; Cyclin-A_N.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   Pfam; PF16500; Cyclin_N2; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           1..426
FT                   /note="G2/mitotic-specific cyclin-A"
FT                   /id="PRO_0000080346"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   426 AA;  48010 MW;  0A590001E3162B37 CRC64;
     MSMVHGSSFQ IAQDGENENQ GVQRVKKAGL TARGNVAVAK RSALGTITNQ NIRVQPSRAA
     KSGNADCQDE NVFAKQKSFG SSNNENKGFK IHVDEPTVQV LTTATLKTTR QSEDEDIKLN
     DQVTSLPSLQ ALEDIQVDNE NGSPMVLDVT IEDAEKKPID REAIILSVPE YAEDIYKHLR
     EAESRHRSKP GYMKKQPDIT NSMRSILVDW MVEVSEEYKL HRETLFLAIN YIDRFLSQMS
     VLRGKLQLVG AASMFIASKY EEIYPPEVSE FVYITDDTYE QKQVLRMEHL ILKVLSFDVA
     QPTINWFTDT YAKMADTDET TKSLSMYLSE LTLVDADPYL KYLPSTIAAA SLCLANITLG
     SEPWPSSLAK ESKYEISEFS ECLQEMYQTY LNAPNHPQQA IREKYKSSKY QQVSSISPPS
     SLSFTM