ID   CCNB2_MACFA             Reviewed;         398 AA.
AC   Q4R7A8;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=G2/mitotic-specific cyclin-B2;
GN   Name=CCNB2; ORFNames=QtsA-15734;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the CDK1 protein kinase to form a
CC       serine/threonine kinase holoenzyme complex also known as maturation
CC       promoting factor (MPF). The cyclin subunit imparts substrate
CC       specificity to the complex (By similarity). {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AB168913; BAE01014.1; -; mRNA.
DR   RefSeq; NP_001270393.1; NM_001283464.1.
DR   AlphaFoldDB; Q4R7A8; -.
DR   SMR; Q4R7A8; -.
DR   STRING; 9541.XP_005559729.1; -.
DR   GeneID; 101925942; -.
DR   CTD; 9133; -.
DR   eggNOG; KOG0653; Eukaryota.
DR   OrthoDB; 993640at2759; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis; Phosphoprotein;
KW   Reference proteome.
FT   CHAIN           1..398
FT                   /note="G2/mitotic-specific cyclin-B2"
FT                   /id="PRO_0000273974"
FT   MOD_RES         8
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         11
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         77
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         92
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         94
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         99
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         392
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
FT   MOD_RES         398
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95067"
SQ   SEQUENCE   398 AA;  45322 MW;  6E613D954533C5E8 CRC64;
     MALLRRPTVS SDLENIDTGF NSKVKSHVTI RRTVLEEIGN KVTTRAAQVA KKAQNTKVPV
     QPTKTTNVNK QLKPTASVKP VQMEMLAPKG PSPTPEDVSM KEENLCQAFS DALLCKIEDI
     DNEDWENPQL CSDYVKDIYQ YLRQLEVLQS INPHFLDGRD INGRMRAILV DWLVQVHSKF
     RLLQETLYMC VAIMDRFLQV QPVSRKKLQL VGITALLLAS KYEEMFSPNI EDFVYITDNA
     YTSSQIREME TLILKELKFE LGRPLPLHFL RRASKAGEVD VEQHTLAKYL MELTLIDYDM
     VHYHPSKVAA AASCLSQKLL GQGKWNLKQQ YYTGYTENEV LEVMQHMAKN VVKVDENLTK
     FIAIKNKYAS SKLLKISTIP QLNSKAVKDL ASPLMGRS